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Spatial Proteomics Reveals Differences in the Cellular Architecture of Antibody-Producing CHO and Plasma Cell–Derived Cells

Most of the recombinant biotherapeutics employed today to combat severe illnesses, for example, various types of cancer or autoimmune diseases, are produced by Chinese hamster ovary (CHO) cells. To meet the growing demand of these pharmaceuticals, CHO cells are under constant development in order to...

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Detalles Bibliográficos
Autores principales: Kretz, Robin, Walter, Larissa, Raab, Nadja, Zeh, Nikolas, Gauges, Ralph, Otte, Kerstin, Fischer, Simon, Stoll, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562429/
https://www.ncbi.nlm.nih.gov/pubmed/35934186
http://dx.doi.org/10.1016/j.mcpro.2022.100278