Metabolic effects of prolactin and the role of dopamine agonists: A review

Prolactin is a polypeptide hormone that is well known for its role in reproductive physiology. Recent studies highlight its role in neurohormonal appetite regulation and metabolism. Elevated prolactin levels are widely associated with worsening metabolic disease, but it appears that low prolactin le...

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Autores principales: Kirsch, Polly, Kunadia, Jessica, Shah, Shruti, Agrawal, Nidhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562454/
https://www.ncbi.nlm.nih.gov/pubmed/36246929
http://dx.doi.org/10.3389/fendo.2022.1002320
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author Kirsch, Polly
Kunadia, Jessica
Shah, Shruti
Agrawal, Nidhi
author_facet Kirsch, Polly
Kunadia, Jessica
Shah, Shruti
Agrawal, Nidhi
author_sort Kirsch, Polly
collection PubMed
description Prolactin is a polypeptide hormone that is well known for its role in reproductive physiology. Recent studies highlight its role in neurohormonal appetite regulation and metabolism. Elevated prolactin levels are widely associated with worsening metabolic disease, but it appears that low prolactin levels could also be metabolically unfavorable. This review discusses the pathophysiology of prolactin related metabolic changes, and the less commonly recognized effects of prolactin on adipose tissue, pancreas, liver, and small bowel. Furthermore, the effect of dopamine agonists on the metabolic profiles of patients with hyperprolactinemia are discussed as well.
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spelling pubmed-95624542022-10-15 Metabolic effects of prolactin and the role of dopamine agonists: A review Kirsch, Polly Kunadia, Jessica Shah, Shruti Agrawal, Nidhi Front Endocrinol (Lausanne) Endocrinology Prolactin is a polypeptide hormone that is well known for its role in reproductive physiology. Recent studies highlight its role in neurohormonal appetite regulation and metabolism. Elevated prolactin levels are widely associated with worsening metabolic disease, but it appears that low prolactin levels could also be metabolically unfavorable. This review discusses the pathophysiology of prolactin related metabolic changes, and the less commonly recognized effects of prolactin on adipose tissue, pancreas, liver, and small bowel. Furthermore, the effect of dopamine agonists on the metabolic profiles of patients with hyperprolactinemia are discussed as well. Frontiers Media S.A. 2022-09-30 /pmc/articles/PMC9562454/ /pubmed/36246929 http://dx.doi.org/10.3389/fendo.2022.1002320 Text en Copyright © 2022 Kirsch, Kunadia, Shah and Agrawal https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Kirsch, Polly
Kunadia, Jessica
Shah, Shruti
Agrawal, Nidhi
Metabolic effects of prolactin and the role of dopamine agonists: A review
title Metabolic effects of prolactin and the role of dopamine agonists: A review
title_full Metabolic effects of prolactin and the role of dopamine agonists: A review
title_fullStr Metabolic effects of prolactin and the role of dopamine agonists: A review
title_full_unstemmed Metabolic effects of prolactin and the role of dopamine agonists: A review
title_short Metabolic effects of prolactin and the role of dopamine agonists: A review
title_sort metabolic effects of prolactin and the role of dopamine agonists: a review
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562454/
https://www.ncbi.nlm.nih.gov/pubmed/36246929
http://dx.doi.org/10.3389/fendo.2022.1002320
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