Humanized Dsp ACM Mouse Model Displays Stress-Induced Cardiac Electrical and Structural Phenotypes

Arrhythmogenic cardiomyopathy (ACM) is an inherited disorder characterized by fibro-fatty infiltration with an increased propensity for ventricular arrhythmias and sudden death. Genetic variants in desmosomal genes are associated with ACM. Incomplete penetrance is a common feature in ACM families, c...

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Detalles Bibliográficos
Autores principales: Stevens, Tyler L., Manring, Heather R., Wallace, Michael J., Argall, Aaron, Dew, Trevor, Papaioannou, Peter, Antwi-Boasiako, Steve, Xu, Xianyao, Campbell, Stuart G., Akar, Fadi G., Borzok, Maegen A., Hund, Thomas J., Mohler, Peter J., Koenig, Sara N., El Refaey, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562631/
https://www.ncbi.nlm.nih.gov/pubmed/36231013
http://dx.doi.org/10.3390/cells11193049

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