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2-Deoxy-D-glucose Alleviates Cancer Cachexia-Induced Muscle Wasting by Enhancing Ketone Metabolism and Inhibiting the Cori Cycle

Cachexia is characterized by progressive weight loss accompanied by the loss of specific skeletal muscle and adipose tissue. Increased lactate production, either due to the Warburg effect from tumors or accelerated glycolysis effects from cachectic muscle, is the most dangerous factor for cancer cac...

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Detalles Bibliográficos
Autores principales: Wei, Lulu, Wang, Ranran, Wazir, Junaid, Lin, Kai, Song, Shiyu, Li, Li, Pu, Wenyuan, Zhao, Chen, Wang, Yong, Su, Zhonglan, Wang, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562633/
https://www.ncbi.nlm.nih.gov/pubmed/36230949
http://dx.doi.org/10.3390/cells11192987

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