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2-Deoxy-D-glucose Alleviates Cancer Cachexia-Induced Muscle Wasting by Enhancing Ketone Metabolism and Inhibiting the Cori Cycle
Cachexia is characterized by progressive weight loss accompanied by the loss of specific skeletal muscle and adipose tissue. Increased lactate production, either due to the Warburg effect from tumors or accelerated glycolysis effects from cachectic muscle, is the most dangerous factor for cancer cac...
Autores principales: | Wei, Lulu, Wang, Ranran, Wazir, Junaid, Lin, Kai, Song, Shiyu, Li, Li, Pu, Wenyuan, Zhao, Chen, Wang, Yong, Su, Zhonglan, Wang, Hongwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562633/ https://www.ncbi.nlm.nih.gov/pubmed/36230949 http://dx.doi.org/10.3390/cells11192987 |
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