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Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma

Genome-wide association studies (GWAS) have shown that variants of patched homolog 1 (PTCH1) are associated with lung function abnormalities in the general population. It has also been shown that sonic hedgehog (SHH), an important ligand for PTCH1, is upregulated in the airway epithelium of patients...

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Detalles Bibliográficos
Autores principales:	Tam, Anthony, Osei, Emmanuel Twumasi, Cheung, Chung Y., Hughes, Michael, Yang, Chen X., McNagny, Kelly M., Dorscheid, Delbert R., Singhera, Gurpreet K., Hallstrand, Teal S., Warner, Stephanie, Hogg, James C., Hackett, Tillie L., Lim, Chinten J., Sin, Don D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562640/ https://www.ncbi.nlm.nih.gov/pubmed/36230980 http://dx.doi.org/10.3390/cells11193016

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