Willin/FRMD6 Mediates Mitochondrial Dysfunction Relevant to Neuronal Aβ Toxicity

Willin/FRMD6 has been reported as a potential Alzheimer’s disease (AD) risk gene in a series of genome-wide association and neuroimaging studies; however, the mechanisms underlying its potential role in AD pathogenesis remain unknown. Here, we demonstrate the direct effects of Aβ on Willin/FRMD6 exp...

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Detalles Bibliográficos
Autores principales: Chen, Doris, Yu, Wanjia, Aitken, Laura, Gunn-Moore, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562665/
https://www.ncbi.nlm.nih.gov/pubmed/36231104
http://dx.doi.org/10.3390/cells11193140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562665/
https://www.ncbi.nlm.nih.gov/pubmed/36231104
http://dx.doi.org/10.3390/cells11193140

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