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Targeting of genomic and negative‐sense strands of viral RNA contributes to antiviral resistance mediated by artificial miRNAs and promotes the emergence of complex viral populations

Technology based on artificial small RNAs, including artificial microRNAs (amiRNAs), exploits natural RNA silencing mechanisms to achieve silencing of endogenous genes or pathogens. This technology has been successfully employed to generate resistance against different eukaryotic viruses. However, i...

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Detalles Bibliográficos
Autores principales: Mesel, Frida, Zhao, Mingmin, García, Beatriz, Simón‐Mateo, Carmen, García, Juan Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562735/
https://www.ncbi.nlm.nih.gov/pubmed/35989243
http://dx.doi.org/10.1111/mpp.13258

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