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Trophoblast Cell Surface Antigen 2 (TROP2) as a Predictive Bio-Marker for the Therapeutic Efficacy of Sacituzumab Govitecan in Adenocarcinoma of the Esophagus

SIMPLE SUMMARY: The trophoblast cell surface antigen 2 (TROP2) is a protein produced by many carcinomas. Sacituzumab govitecan (SG) is a drug consisting of an antibody that binds to TROP2 on the tumor cell when TROP2 is present and is taken up into the cell interior after binding. The antibody is co...

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Detalles Bibliográficos
Autores principales:	Hoppe, Sascha, Meder, Lydia, Gebauer, Florian, Ullrich, Roland T., Zander, Thomas, Hillmer, Axel M., Buettner, Reinhard, Plum, Patrick, Puppe, Julian, Malter, Wolfram, Quaas, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562858/ https://www.ncbi.nlm.nih.gov/pubmed/36230712 http://dx.doi.org/10.3390/cancers14194789

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