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Visceral Adipose Tissue E2F1-miRNA206/210 Pathway Associates with Type 2 Diabetes in Humans with Extreme Obesity

Objective: Up-regulated expression of transcription-factor E2F1 in human visceral adipose tissue (VAT) characterizes a dysmetabolic obesity sub-phenotype. An E2F1-miRNA network has been described in multiple cancers. Here we investigated whether elevated VAT-E2F1 in obesity is associated with VAT-mi...

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Detalles Bibliográficos
Autores principales: Maixner, Nitzan, Haim, Yulia, Blüher, Matthias, Chalifa-Caspi, Vered, Veksler-Lublinsky, Isana, Makarenkov, Nataly, Yoel, Uri, Bashan, Nava, Liberty, Idit F., Kukeev, Ivan, Dukhno, Oleg, Levy, Dan, Rudich, Assaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562862/
https://www.ncbi.nlm.nih.gov/pubmed/36231008
http://dx.doi.org/10.3390/cells11193046