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Preclinical Efficacy and Toxicology Evaluation of RAC1 Inhibitor 1A-116 in Human Glioblastoma Models

SIMPLE SUMMARY: Malignant gliomas are the most common primary central nervous system tumors in adults. Currently, this disease is associated with poor prognosis and is virtually incurable. There is a need to find novel targets and treatments to improve patient survival. This study shows the preclini...

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Detalles Bibliográficos
Autores principales:	Cardama, Georgina A., Maggio, Julian, Valdez Capuccino, Lucas, Gonzalez, Nazareno, Matiller, Valentina, Ortega, Hugo H., Perez, German R., Demarco, Ignacio A., Spitzer, Eduardo, Gomez, Daniel E., Lorenzano Menna, Pablo, Alonso, Daniel F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562863/ https://www.ncbi.nlm.nih.gov/pubmed/36230732 http://dx.doi.org/10.3390/cancers14194810

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