Sustained Infiltration of Neutrophils Into the CNS Results in Increased Demyelination in a Viral-Induced Model of Multiple Sclerosis

Intracranial inoculation of the neuroadapted JHM strain of mouse hepatitis virus (JHMV) into susceptible strains of mice results in acute encephalomyelitis followed by a cimmune-mediated demyelination similar to the human demyelinating disease multiple sclerosis (MS). JHMV infection of transgenic mi...

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Detalles Bibliográficos
Autores principales: Skinner, Dominic D., Syage, Amber R., Olivarria, Gema M., Stone, Colleen, Hoglin, Bailey, Lane, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562915/
https://www.ncbi.nlm.nih.gov/pubmed/36248905
http://dx.doi.org/10.3389/fimmu.2022.931388

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