Genetic susceptibility loci for Chlamydia trachomatis endometrial infection influence expression of genes involved in T cell function, tryptophan metabolism and epithelial integrity

OBJECTIVES: Identify genetic loci of enhanced susceptibility to Chlamydial trachomatis (Ct) upper genital tract infection in women. METHODS: We performed an integrated analysis of DNA genotypes and blood-derived mRNA profiles from 200 Ct-exposed women to identify expression quantitative trait loci (...

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Detalles Bibliográficos
Autores principales: Zhong, Wujuan, Kollipara, Avinash, Liu, Yutong, Wang, Yuhan, O’Connell, Catherine M., Poston, Taylor B., Yount, Kacy, Wiesenfeld, Harold C., Hillier, Sharon L., Li, Yun, Darville, Toni, Zheng, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562917/
https://www.ncbi.nlm.nih.gov/pubmed/36248887
http://dx.doi.org/10.3389/fimmu.2022.1001255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562917/
https://www.ncbi.nlm.nih.gov/pubmed/36248887
http://dx.doi.org/10.3389/fimmu.2022.1001255

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