Restored Fyn Levels in Huntington’s Disease Contributes to Enhanced Synaptic GluN2B-Composed NMDA Receptors and CREB Activity

N-methyl-D-aspartate receptors (NMDARs) are important postsynaptic receptors that contribute to normal synaptic function and cell survival; however, when overactivated, as in Huntington’s disease (HD), NMDARs cause excitotoxicity. HD-affected striatal neurons show altered NMDAR currents and augmente...

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Detalles Bibliográficos
Autores principales: Fão, Lígia, Coelho, Patrícia, Rodrigues, Ricardo J., Rego, A. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563007/
https://www.ncbi.nlm.nih.gov/pubmed/36231023
http://dx.doi.org/10.3390/cells11193063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563007/
https://www.ncbi.nlm.nih.gov/pubmed/36231023
http://dx.doi.org/10.3390/cells11193063

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