Cargando…

Cholesterol-Inulin Conjugates for Efficient SN38 Nuclear Delivery: Nanomedicines for Precision Cancer Therapy

SIMPLE SUMMARY: Severe limitations of conventional chemotherapy including unspecific biodistribution both at the tissue and cell organelle level have led to the necessity of developing precise and personalized therapeutic strategies. Accordingly, nanomedicine has aroused increased attention due to t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mauro, Nicolò, Utzeri, Mara Andrea, Cillari, Roberta, Scialabba, Cinzia, Giammona, Gaetano, Cavallaro, Gennara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563076/ https://www.ncbi.nlm.nih.gov/pubmed/36230779 http://dx.doi.org/10.3390/cancers14194857

Ejemplares similares

Gadolinium-Doped Carbon Nanodots as Potential Anticancer Tools for Multimodal Image-Guided Photothermal Therapy and Tumor Monitoring
por: Mauro, Nicolò, et al.
Publicado: (2023)

Carbon Nanodots as Functional Excipient to Develop Highly Stable and Smart PLGA Nanoparticles Useful in Cancer Theranostics
por: Mauro, Nicolò, et al.
Publicado: (2020)

Pressure-Dependent Tuning of Photoluminescence and Size Distribution of Carbon Nanodots for Theranostic Anticancer Applications
por: Mauro, Nicolò, et al.
Publicado: (2020)

Carbon Nanodots for On Demand Chemophotothermal Therapy Combination to Elicit Necroptosis: Overcoming Apoptosis Resistance in Breast Cancer Cell Lines
por: Nicosia, Aldo, et al.
Publicado: (2020)

Inhalable Formulation Based on Lipid–Polymer Hybrid Nanoparticles for the Macrophage Targeted Delivery of Roflumilast
por: Craparo, Emanuela F., et al.
Publicado: (2022)

Development of New Targeted Inulin Complex Nanoaggregates for siRNA Delivery in Antitumor Therapy
por: Cavallaro, Gennara, et al.
Publicado: (2021)

Combining Inulin Multifunctional Polycation and Magnetic Nanoparticles: Redox-Responsive siRNA-Loaded Systems for Magnetofection
por: Sardo, Carla, et al.
Publicado: (2019)

Functionalization of Metal and Carbon Nanoparticles with Potential in Cancer Theranostics
por: Mauro, Nicolò, et al.
Publicado: (2021)

Design of New Polyaspartamide Copolymers for siRNA Delivery in Antiasthmatic Therapy
por: Craparo, Emanuela Fabiola, et al.
Publicado: (2020)

Margination of Fluorescent Polylactic Acid–Polyaspartamide based Nanoparticles in Microcapillaries In Vitro: the Effect of Hematocrit and Pressure
por: Craparo, Emanuela Fabiola, et al.
Publicado: (2017)

Polyaspartamide-Based Nanoparticles Loaded with Fluticasone Propionate and the In Vitro Evaluation towards Cigarette Smoke Effects
por: Craparo, Emanuela Fabiola, et al.
Publicado: (2017)

Rapamycin-Loaded Polymeric Nanoparticles as an Advanced Formulation for Macrophage Targeting in Atherosclerosis
por: Craparo, Emanuela Fabiola, et al.
Publicado: (2021)

Inulin-Based Polymeric Micelles Functionalized with Ocular Permeation Enhancers: Improvement of Dexamethasone Permeation/Penetration through Bovine Corneas
por: Di Prima, Giulia, et al.
Publicado: (2021)

Inulin coated plasmonic gold nanoparticles as a tumor-selective tool for cancer therapy
por: Li Volsi, Anna, et al.
Publicado: (2016)

Effects in cigarette smoke stimulated bronchial epithelial cells of a corticosteroid entrapped into nanostructured lipid carriers
por: Bondì, Maria Luisa, et al.
Publicado: (2014)

Carbon dots conjugated to SN38 for improved colorectal anticancer therapy
por: Mattinzoli, Deborah, et al.
Publicado: (2022)

Synthesis and Antitumor Evaluation of Biotin-SN38-Valproic Acid Conjugates
por: Dai, Yi, et al.
Publicado: (2023)

On the design of precision nanomedicines
por: Tian, Xiaohe, et al.
Publicado: (2020)

Conjugation of Inulin Improves Anti-Biofilm Activity of Chitosan
por: Zhang, Guiqiang, et al.
Publicado: (2018)

Synthesis and evaluation of highly releasable and structurally stable antibody-SN-38-conjugates
por: Liu, Lianqi, et al.
Publicado: (2021)

Effect of the prebiotic fiber inulin on cholesterol metabolism in wildtype mice
por: Mistry, Rima H., et al.
Publicado: (2018)

Synthesis of Biocompatible and Biodegradable Polyamidoamines Microgels via a Simple and Reliable Statistical Approach
por: Mauro, Nicolò, et al.
Publicado: (2022)

Harnessing RNAi nanomedicine for precision therapy
por: Peer, Dan
Publicado: (2014)

Biomimetic nanomedicines for precise atherosclerosis theranostics
por: Tao, Ying, et al.
Publicado: (2023)

Human Serum Albumin Conjugates of 7-Ethyl-10-hydroxycamptothecin (SN38) for Cancer Treatment
por: Sepehri, Nima, et al.
Publicado: (2014)

Research Progress of Conjugated Nanomedicine for Cancer Treatment
por: Zhao, Bin, et al.
Publicado: (2022)

Precise design of nanomedicines: perspectives for cancer treatment
por: Wang, Jing, et al.
Publicado: (2019)

Investigation into the Efficacy of Val-SN-38, a Valine-Ester Prodrug of the Anti-Cancer Agent SN-38
por: Kwak, Eun-Young, et al.
Publicado: (2012)

Special Issue “Recent Advances in Precision Nanomedicine for Cancer”
por: Brignole, Chiara, et al.
Publicado: (2020)

Aptamer-Equipped Protamine Nanomedicine for Precision Lymphoma Therapy
por: Zeng, Zihua, et al.
Publicado: (2020)

Engineering Tumor-Targeting Nanoparticles as Vehicles for Precision Nanomedicine
por: Gonda, Amber, et al.
Publicado: (2019)

Design and Characterization of Inulin Conjugate for Improved Intracellular and Targeted Delivery of Pyrazinoic Acid to Monocytes
por: Afinjuomo, Franklin, et al.
Publicado: (2019)

Synthesis and Characterization of pH-Sensitive Inulin Conjugate of Isoniazid for Monocyte-Targeted Delivery
por: Afinjuomo, Franklin, et al.
Publicado: (2019)

mPEG-PLGA Nanoparticles Labelled with Loaded or Conjugated Rhodamine-B for Potential Nose-to-Brain Delivery
por: Craparo, Emanuela Fabiola, et al.
Publicado: (2021)

An EGFR inhibitor enhances the efficacy of SN38, an active metabolite of irinotecan, in SN38-refractory gastric carcinoma cells
por: Yashiro, M, et al.
Publicado: (2011)

Synthesis, characterization, and evaluation of mPEG–SN38 and mPEG–PLA–SN38 micelles for cancer therapy
por: Xie, Jing, et al.
Publicado: (2016)

Inulin Supplementation Disturbs Hepatic Cholesterol and Bile Acid Metabolism Independent from Housing Temperature
por: Pauly, Mira J., et al.
Publicado: (2020)

Comparison of two self-assembled macromolecular prodrug micelles with different conjugate positions of SN38 for enhancing antitumor activity
por: Liu, Yi, et al.
Publicado: (2015)

Development of Self-Associating SN-38-Conjugated Poly(ethylene oxide)-Poly(ester) Micelles for Colorectal Cancer Therapy
por: Sadat, Sams M. A., et al.
Publicado: (2020)

Does sacituzumab-govitecan act as a conventional antibody drug conjugate (ADC), a prodrug of SN-38 or both?
por: Santi, Daniel V., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6r029pbf0ql47bvlnevr970n9o