A Novel Bayesian Framework Infers Driver Activation States and Reveals Pathway-Oriented Molecular Subtypes in Head and Neck Cancer

SIMPLE SUMMARY: Numerous factors, such as genomic mutations, chromosomal changes, transcriptional controls, phosphorylation, and protein–protein interactions, among others, can affect the activation status of proteins. Although each data type only partially reveals the status of a particular gene’s...

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Detalles Bibliográficos
Autores principales: Liu, Zhengping, Cai, Chunhui, Ma, Xiaojun, Liu, Jinling, Chen, Lujia, Lui, Vivian Wai Yan, Cooper, Gregory F., Lu, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563147/
https://www.ncbi.nlm.nih.gov/pubmed/36230748
http://dx.doi.org/10.3390/cancers14194825

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