ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway

Pancreatic adenocarcinoma (PAAD) is one of the most aggressive digestive system tumors in the world, with a low early diagnosis rate and a high mortality. Integrin beta 5 (ITGB5) is demonstrated to be a potent tumor promoter in several carcinomas. However, it is unknown whether ITGB5 participates in...

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Autores principales: Wen, Xin, Chen, Si, Chen, Xueting, Qiu, Hui, Wang, Wei, Zhang, Nie, Liu, Wanming, Wang, Tingting, Ding, Xin, Zhang, Longzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563233/
https://www.ncbi.nlm.nih.gov/pubmed/36249018
http://dx.doi.org/10.3389/fonc.2022.887068

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