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In Vitro Selection of Macrocyclic α/β(3)-Peptides against Human EGFR

[Image: see text] Here, we report ribosomal construction of thioether-macrocyclic α/β(3)-peptide libraries in which β-homoglycine, β-homoalanine, β-homophenylglycine, and β-homoglutamine are introduced by genetic code reprogramming. The libraries were applied to the RaPID (Random nonstandard Peptide...

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Detalles Bibliográficos
Autores principales:	Wakabayashi, Risa, Kawai, Marina, Katoh, Takayuki, Suga, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563295/ https://www.ncbi.nlm.nih.gov/pubmed/36173923 http://dx.doi.org/10.1021/jacs.2c07624

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