Cargando…

Stage-Dependent Activity and Pro-Chondrogenic Function of PI3K/AKT during Cartilage Neogenesis from Mesenchymal Stromal Cells

Differentiating mesenchymal stromal cells (MSCs) into articular chondrocytes (ACs) for application in clinical cartilage regeneration requires a profound understanding of signaling pathways regulating stem cell chondrogenesis and hypertrophic degeneration. Classifying endochondral signals into drive...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klampfleuthner, Felicia A. M., Lotz, Benedict, Renkawitz, Tobias, Richter, Wiltrud, Diederichs, Solvig
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563299/ https://www.ncbi.nlm.nih.gov/pubmed/36230927 http://dx.doi.org/10.3390/cells11192965

Ejemplares similares

Inverse Regulation of Cartilage Neogenesis at Physiologically Relevant Calcium Conditions by Human Articular Chondrocytes and Mesenchymal Stromal Cells
por: Hammersen, Tim, et al.
Publicado: (2023)

Chondral Differentiation of Induced Pluripotent Stem Cells Without Progression Into the Endochondral Pathway
por: Diederichs, Solvig, et al.
Publicado: (2019)

NFκB inhibition to lift the mechano-competence of mesenchymal stromal cell-derived neocartilage toward articular chondrocyte levels
por: Lückgen, Janine, et al.
Publicado: (2022)

The Role of Extracellular Matrix Expression, ERK1/2 Signaling and Cell Cohesiveness for Cartilage Yield from iPSCs
por: Buchert, Justyna, et al.
Publicado: (2019)

Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Cells
por: Kreuser, Ursula, et al.
Publicado: (2020)

Significance of MEF2C and RUNX3 Regulation for Endochondral Differentiation of Human Mesenchymal Progenitor Cells
por: Dreher, Simon I., et al.
Publicado: (2020)

Different culture media affect growth characteristics, surface marker distribution and chondrogenic differentiation of human bone marrow-derived mesenchymal stromal cells
por: Hagmann, Sebastien, et al.
Publicado: (2013)

Treatment of Focal Cartilage Defects in Minipigs with Zonal Chondrocyte/Mesenchymal Progenitor Cell Constructs
por: Bothe, Friederike, et al.
Publicado: (2019)

MiR-181a Targets RSPO2 and Regulates Bone Morphogenetic Protein – WNT Signaling Crosstalk During Chondrogenic Differentiation of Mesenchymal Stromal Cells
por: Melnik, Svitlana, et al.
Publicado: (2021)

„Platelet-rich plasma“ (PRP): Analyse der Zusammensetzung bei unterschiedlichem Ernährungsverhalten und Blutentnahmezeitpunkt
por: Platzer, Hadrian, et al.
Publicado: (2023)

Lymphoid neogenesis in chronic inflammation
por: Pitzalis, C, et al.
Publicado: (2003)

Differences in the intrinsic chondrogenic potential of equine umbilical cord matrix and cord blood mesenchymal stromal/stem cells for cartilage regeneration
por: Rakic, Rodolphe, et al.
Publicado: (2018)

Bioluminescence Assays for Monitoring Chondrogenic Differentiation and Cartilage Regeneration
por: Je, Hyeon Jeong, et al.
Publicado: (2017)

Directed differentiation of induced pluripotent stem cells into chondrogenic lineages for articular cartilage treatment
por: Lach, Michał, et al.
Publicado: (2014)

Preclinical Testing of New Hydrogel Materials for Cartilage Repair: Overcoming Fixation Issues in a Large Animal Model
por: Lotz, Benedict, et al.
Publicado: (2021)

Factors controlling pancreatic islet neogenesis.
por: Vinik, A., et al.
Publicado: (1992)

Ultra-structural changes and expression of chondrogenic and hypertrophic genes during chondrogenic differentiation of mesenchymal stromal cells in alginate beads
por: Dashtdar, Havva, et al.
Publicado: (2016)

Synthesis, Biological Evaluation, and Docking Studies of a Novel Sulfonamido-Based Gallate as Pro-Chondrogenic Agent for the Treatment of Cartilage
por: Lin, Xiao, et al.
Publicado: (2016)

Conversion of senescent cartilage into a pro-chondrogenic microenvironment with antibody-functionalized copper sulfate nanoparticles for efficient osteoarthritis therapy
por: Wang, Xianming, et al.
Publicado: (2023)

Publisher Correction: Differences in the intrinsic chondrogenic potential of equine umbilical cord matrix and cord blood mesenchymal stromal/stem cells for cartilage regeneration
por: Rakic, Rodolphe, et al.
Publicado: (2020)

New Perspectives in Chondrogenic Differentiation of Stem Cells for Cartilage Repair
por: Toh, Wei Seong, et al.
Publicado: (2006)

Ex Vivo Systems to Study Chondrogenic Differentiation and Cartilage Integration
por: Monaco, Graziana, et al.
Publicado: (2021)

Effects of In Vitro Low Oxygen Tension Preconditioning of Adipose Stromal Cells on Their In Vivo Chondrogenic Potential: Application in Cartilage Tissue Repair
por: Portron, Sophie, et al.
Publicado: (2013)

Irisin enhances chondrogenic differentiation of human mesenchymal stem cells via Rap1/PI3K/AKT axis
por: Chen, Taiqiu, et al.
Publicado: (2022)

Chondrogenic differentiation of mesenchymal stem cells through cartilage matrix-inspired surface coatings
por: Zhao, Mingyan, et al.
Publicado: (2022)

Enhanced chondrogenic differentiation of iPS cell-derived mesenchymal stem/stromal cells via neural crest cell induction for hyaline cartilage repair
por: Zujur, Denise, et al.
Publicado: (2023)

Review: Pancreatic β-Cell Neogenesis Revisited
por: Paris, Maryline, et al.
Publicado: (2004)

Chronic inflammation caused by lymphotoxin is lymphoid neogenesis
Publicado: (1996)

Differential Regulation of circRNA, miRNA, and piRNA during Early Osteogenic and Chondrogenic Differentiation of Human Mesenchymal Stromal Cells
por: Della Bella, Elena, et al.
Publicado: (2020)

RGD-Functionalized Hydrogel Supports the Chondrogenic Commitment of Adipose Mesenchymal Stromal Cells
por: Manferdini, Cristina, et al.
Publicado: (2022)

Gene Expression and Chondrogenic Potential of Cartilage Cells: Osteoarthritis Grade Differences
por: Mazor, Marija, et al.
Publicado: (2022)

Impact of c-MYC expression on proliferation, differentiation, and risk of neoplastic transformation of human mesenchymal stromal cells
por: Melnik, Svitlana, et al.
Publicado: (2019)

Integration of Bioglass Into PHBV-Constructed Tissue-Engineered Cartilages to Improve Chondrogenic Properties of Cartilage Progenitor Cells
por: Xue, Ke, et al.
Publicado: (2022)

Synergistic effects on mesenchymal stem cell-based cartilage regeneration by chondrogenic preconditioning and mechanical stimulation
por: Lin, Sien, et al.
Publicado: (2017)

Comparative in vitro treatment of mesenchymal stromal cells with GDF-5 and R57A induces chondrogenic differentiation while limiting chondrogenic hypertrophy
por: Weißenberger, Manuel, et al.
Publicado: (2023)

Characterisation of ovine bone marrow-derived stromal cells (oBMSC) and evaluation of chondrogenically induced micro-pellets for cartilage tissue repair in vivo
por: Futrega, K., et al.
Publicado: (2021)

Nutrient Excess Stimulates β-Cell Neogenesis in Zebrafish
por: Maddison, Lisette A., et al.
Publicado: (2012)

The pathological features of ectopic lymphoid neogenesis in idiopathic dacryoadenitis
por: Guo, Jie, et al.
Publicado: (2016)

Lymphoid Neogenesis and Tertiary Lymphoid Organs in Transplanted Organs
por: Koenig, Alice, et al.
Publicado: (2016)

Lymphoid neogenesis in melanoma: What does it tell us?
por: van Baren, Nicolas, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_nmod07hofj9kf3j3m28ctmfm3e