Fast and high-throughput LC-MS characterization, and peptide mapping of engineered AAV capsids using LC-MS/MS

Adeno-associated virus (AAV) has emerged as a leading platform for gene therapy. With the skyrocketing rate of AAV research and the prevalence of many new engineered capsids being investigated in preclinical and clinical trials, capsid characterization plays a vital role in serotype confirmation and...

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Detalles Bibliográficos
Autores principales: Lam, Anh K., Zhang, Junping, Frabutt, Dylan, Mulcrone, Patrick L., Li, Lei, Zeng, Lifan, Herzog, Roland W., Xiao, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563341/
https://www.ncbi.nlm.nih.gov/pubmed/36284765
http://dx.doi.org/10.1016/j.omtm.2022.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563341/
https://www.ncbi.nlm.nih.gov/pubmed/36284765
http://dx.doi.org/10.1016/j.omtm.2022.09.008

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