Cargando…
Combination of Paclitaxel and PXR Antagonist SPA70 Reverses Paclitaxel-Resistant Non-Small Cell Lung Cancer
Paclitaxel (PTX) is one of the most efficient drugs for late-stage non-small cell lung cancer (NSCLC) patients. However, most patients gradually develop resistance to PTX with long-term treatments. The identification of new strategies to reverse PTX resistance in NSCLC is crucially important for the...
Autores principales: | Niu, Xiaxia, Wu, Ting, Yin, Qishuang, Gu, Xinsheng, Li, Gege, Zhou, Changlong, Ma, Mei, Su, Li, Tang, Shu, Tian, Yanan, Yang, Ming, Cui, Hongmei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563422/ https://www.ncbi.nlm.nih.gov/pubmed/36231056 http://dx.doi.org/10.3390/cells11193094 |
Ejemplares similares
-
Insights into the critical role of the PXR in preventing carcinogenesis and chemotherapeutic drug resistance
por: Niu, Xiaxia, et al.
Publicado: (2022) -
Nuclear Receptor PXR Confers Irradiation Resistance by Promoting DNA Damage Response Through Stabilization of ATF3
por: Niu, Xiaxia, et al.
Publicado: (2022) -
SPA70 is a potent antagonist of human pregnane X receptor
por: Lin, Wenwei, et al.
Publicado: (2017) -
Centrosomal Protein 70 Is a Mediator of Paclitaxel Sensitivity
por: Shi, Xingjuan, et al.
Publicado: (2017) -
CRM197 reverses paclitaxel resistance by inhibiting the NAC‐1/Gadd45 pathway in paclitaxel‐resistant ovarian cancer cells
por: Tang, Xiao‐han, et al.
Publicado: (2019)