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The Immunocytokine FAP-IL-2v Enhances Anti-Neuroblastoma Efficacy of the Anti-GD(2) Antibody Dinutuximab Beta
SIMPLE SUMMARY: Since IL-2 co-treatment did not show any therapeutic benefit in the GD(2)-directed treatment of high-risk neuroblastoma (NB) but strongly induced regulatory T cells (Treg), we investigated here the immunocytokine FAP-IL-2v stimulating NK and cytotoxic T cells without induction of Tre...
Autores principales: | Siebert, Nikolai, Leopold, Justus, Zumpe, Maxi, Troschke-Meurer, Sascha, Biskupski, Simon, Zikoridse, Alexander, Lode, Holger N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563425/ https://www.ncbi.nlm.nih.gov/pubmed/36230765 http://dx.doi.org/10.3390/cancers14194842 |
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