Cargando…

NR2F1 Regulates TGF-β1-Mediated Epithelial-Mesenchymal Transition Affecting Platinum Sensitivity and Immune Response in Ovarian Cancer

SIMPLE SUMMARY: In ovarian cancer (OC), platinum-based therapy remains the front-line therapy, but drug resistance is common. In the current study, we analyzed two Gene Expression Omnibus (GEO) datasets to identify the responsible genes involved in the mechanism of platinum resistance. Thirteen co-u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Qiuju, Xu, Zhijie, Liu, Yuanhong, Peng, Bi, Cai, Yuan, Liu, Wei, Yan, Yuanliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563458/ https://www.ncbi.nlm.nih.gov/pubmed/36230565 http://dx.doi.org/10.3390/cancers14194639

Ejemplares similares

Drug metabolism-related gene ABCA1 augments temozolomide chemoresistance and immune infiltration abundance of M2 macrophages in glioma
por: Yan, Yuanliang, et al.
Publicado: (2023)

Platinum-resistance in epithelial ovarian cancer: an interplay of epithelial–mesenchymal transition interlinked with reprogrammed metabolism
por: Leung, Dilys, et al.
Publicado: (2022)

NR1D2 Accelerates Hepatocellular Carcinoma Progression by Driving the Epithelial-to-Mesenchymal Transition
por: Tong, Hui, et al.
Publicado: (2020)

Targeting RAS guanyl releasing protein 1 promotes T lymphocytes infiltrations and improves anti‐programmed death receptor ligand 1 therapy response of triple‐negative breast cancer
por: Chen, Xi, et al.
Publicado: (2023)

Fbxo21 regulates the epithelial-to-mesenchymal transition through ubiquitination of Nr2f2 in gastric cancer
por: Jiang, Yannan, et al.
Publicado: (2021)

Metal-organic framework-encapsulated dihydroartemisinin nanoparticles induces apoptotic cell death in ovarian cancer by blocking ROMO1-mediated ROS production
por: Yan, Yuanliang, et al.
Publicado: (2023)

HPIP Silencing Prevents Epithelial–Mesenchymal Transition Induced by TGF-β1 in Human Ovarian Cancer Cells
por: Zhang, Guo-ying, et al.
Publicado: (2016)

Non-coding RNAs: The recently accentuated molecules in the regulation of cell autophagy for ovarian cancer pathogenesis and therapeutic response
por: Peng, Bi, et al.
Publicado: (2023)

TGFβ1 in fibroblasts-derived exosomes promotes epithelial-mesenchymal transition of ovarian cancer cells
por: Li, Wenqian, et al.
Publicado: (2017)

Myricetin suppresses TGF-β-induced epithelial-to-mesenchymal transition in ovarian cancer
por: Yang, Hui-Wen, et al.
Publicado: (2023)

Andrographolide attenuates epithelial‐mesenchymal transition induced by TGF‐β1 in alveolar epithelial cells
por: Li, Jingpei, et al.
Publicado: (2020)

A combined analysis of bulk and single-cell sequencing data reveals metabolic enzyme, pyruvate dehydrogenase E1 subunit beta (PDHB), as a prediction biomarker for the tumor immune response and immunotherapy
por: Zhang, Fan, et al.
Publicado: (2023)

NR4A1 inhibits the epithelial–mesenchymal transition of hepatic stellate cells: Involvement of TGF-β–Smad2/3/4–ZEB signaling
por: Huang, Qian, et al.
Publicado: (2022)

NR2F2 plays a major role in insulin-induced epithelial-mesenchymal transition in breast cancer cells
por: Xia, Baili, et al.
Publicado: (2020)

Current insights into the functional roles of ferroptosis in musculoskeletal diseases and therapeutic implications
por: Zhang, Fan, et al.
Publicado: (2023)

PTPN13 Participates in the Regulation of Epithelial–Mesenchymal Transition and Platinum Sensitivity in High-Grade Serous Ovarian Carcinoma Cells
por: Aptecar, Leticia, et al.
Publicado: (2023)

SIX1 coordinates with TGFβ signals to induce epithelial-mesenchymal transition in cervical cancer
por: Sun, Shu-Hua, et al.
Publicado: (2016)

Hic-5 regulates epithelial to mesenchymal transition in ovarian cancer cells in a TGFβ1-independent manner
por: Sheta, Razan, et al.
Publicado: (2017)

Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition
por: Jiang, Lei, et al.
Publicado: (2014)

The mechanism of epithelial-mesenchymal transition induced by TGF-β1 in neuroblastoma cells
por: Shao, Jing-Bo, et al.
Publicado: (2017)

Role of TGF-β1-mediated epithelial-mesenchymal transition in the pathogenesis of tympanosclerosis
por: Qiu, Jingjing, et al.
Publicado: (2021)

DNMTs Are Involved in TGF-β1-Induced Epithelial–Mesenchymal Transitions in Airway Epithelial Cells
por: Park, Joo-Hoo, et al.
Publicado: (2022)

Effects of bradykinin on TGF-β1-induced epithelial-mesenchymal transition in ARPE-19 cells
por: Wei, Qingquan, et al.
Publicado: (2018)

Mechanisms of TGFβ-Induced Epithelial–Mesenchymal Transition
por: Moustakas, Aristidis, et al.
Publicado: (2016)

Apolipoprotein A1 Inhibits TGF-β1–Induced Epithelial-to-Mesenchymal Transition of Alveolar Epithelial Cells
por: Baek, Ae Rin, et al.
Publicado: (2016)

FHOD1 is upregulated in glioma cells and attenuates ferroptosis of glioma cells by targeting HSPB1 signaling
por: Zhang, Fan, et al.
Publicado: (2023)

Epithelial–Mesenchymal Transition in Ovarian Carcinoma
por: Davidson, Ben, et al.
Publicado: (2012)

IL-27 inhibits the TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells
por: Dong, Zhaoxing, et al.
Publicado: (2016)

The platinum coordination complex inhibits cell invasion-migration and epithelial-to-mesenchymal transition by altering the TGF-β-SMAD pathway in colorectal cancer
por: Abdulla, Maha-Hamadien, et al.
Publicado: (2023)

TGF-β1 induces human alveolar epithelial to mesenchymal cell transition (EMT)
por: Kasai, Hidenori, et al.
Publicado: (2005)

Downregulated ADARB1 Facilitates Cell Proliferation, Invasion and has Effect on the Immune Regulation in Ovarian Cancer
por: Zhu, Wei, et al.
Publicado: (2021)

Unraveling the significance of exosomal circRNAs in cancer therapeutic resistance
por: Kang, Fanhua, et al.
Publicado: (2023)

DNMT1 Regulates IL-6- and TGF-β1-Induced Epithelial Mesenchymal Transition in Prostate Epithelial Cells
por: Xu, Hui, et al.
Publicado: (2017)

Spectrum of Mesenchymal–Epithelial Transition Aberrations and Potential Clinical Implications: Insights From Integrative Pancancer Analysis
por: Li, Juanni, et al.
Publicado: (2020)

Requirement of Podocalyxin in TGF-Beta Induced Epithelial Mesenchymal Transition
por: Meng, Xiaobo, et al.
Publicado: (2011)

Formin-dependent TGF-β signaling for epithelial to mesenchymal transition
por: Rana, Manish K., et al.
Publicado: (2018)

TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis
por: Hao, Yang, et al.
Publicado: (2019)

GOLM1 Promotes Epithelial-Mesenchymal Transition by Activating TGFβ1/Smad2 Signaling in Prostate Cancer
por: Qin, Xuke, et al.
Publicado: (2023)

KRT7 promotes epithelial-mesenchymal transition in ovarian cancer via the TGF-β/Smad2/3 signaling pathway
por: An, Qiang, et al.
Publicado: (2021)

CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression
por: Liang, Qian, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_32tfbt98b8p3n0bu2jtuvb6s7q