The Distinctive Activation of Toll-Like Receptor 4 in Human Samples with Sepsis

Clinical success of Toll-Like receptor-4 (TLR-4) antagonists in sepsis therapy has thus far been lacking. As inhibition of a receptor can only be useful if the receptor is active, stratification of patients with active TLR-4 would be desirable. Our aim was to establish an assay to quantify phosphory...

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Detalles Bibliográficos
Autores principales: Thon, Patrick, Rump, Katharina, Knorr, Annika, Dyck, Birte, Ziehe, Dominik, Unterberg, Matthias, Nowak, Hartmuth, Bergmann, Lars, Wolf, Alexander, Bazzi, Maha, Orlowski, Jennifer, Peters, Marcus, Zarbock, Alexander, Brenner, Thorsten, Adamzik, Michael, Rahmel, Tim, Koos, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563554/
https://www.ncbi.nlm.nih.gov/pubmed/36230982
http://dx.doi.org/10.3390/cells11193020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563554/
https://www.ncbi.nlm.nih.gov/pubmed/36230982
http://dx.doi.org/10.3390/cells11193020

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