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Proteomics and phosphoproteomics of chordoma biopsies reveal alterations in multiple pathways and aberrant kinases activities

BACKGROUND: Chordoma is a slow-growing but malignant subtype of bone sarcoma with relatively high recurrence rates and high resistance to chemotherapy. It is urgent to understand the underlying regulatory networks to determine more effective potential targets. Phosphorylative regulation is currently...

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Detalles Bibliográficos
Autores principales:	Hang, Jing, Ouyang, Hanqiang, Wei, Feng, Zhong, Qihang, Yuan, Wanqiong, Jiang, Liang, Liu, Zhongjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563620/ https://www.ncbi.nlm.nih.gov/pubmed/36248973 http://dx.doi.org/10.3389/fonc.2022.941046

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