Double cytoplast embryonic cloning improves in vitro but not in vivo development from mitotic pluripotent cells in cattle

Cloning multiple animals from genomically selected donor embryos is inefficient but would accelerate genetic gain in dairy cattle breeding. To improve embryo cloning efficiency, we explored the idea that epigenetic reprogramming improves when donor cells are in mitosis. We derived primary cultures f...

Descripción completa

Detalles Bibliográficos
Autores principales: Appleby, Sarah Jane, Misica‐Turner, Pavla, Oback, Fleur Catherine, Dhali, Arindam, McLean, Zachariah Louis, Oback, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563626/
https://www.ncbi.nlm.nih.gov/pubmed/36246653
http://dx.doi.org/10.3389/fgene.2022.933534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563626/
https://www.ncbi.nlm.nih.gov/pubmed/36246653
http://dx.doi.org/10.3389/fgene.2022.933534

Ejemplares similares