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Double cytoplast embryonic cloning improves in vitro but not in vivo development from mitotic pluripotent cells in cattle
Cloning multiple animals from genomically selected donor embryos is inefficient but would accelerate genetic gain in dairy cattle breeding. To improve embryo cloning efficiency, we explored the idea that epigenetic reprogramming improves when donor cells are in mitosis. We derived primary cultures f...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563626/ https://www.ncbi.nlm.nih.gov/pubmed/36246653 http://dx.doi.org/10.3389/fgene.2022.933534 |