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Learning from maternal deaths due to uterine rupture: review of cases from peri-urban Uganda
BACKGROUND: Maternal deaths from uterine rupture continue to occur globally, with particularly high rates in sub-Saharan Africa. Maternal death reviews have been shown to be an effective part of cohesive strategies to prevent future deaths. OBJECTIVE: This study aimed to conduct maternal death revie...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563662/ https://www.ncbi.nlm.nih.gov/pubmed/36276797 http://dx.doi.org/10.1016/j.xagr.2022.100063 |
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author | Namagembe, Imelda Chukwuma, Sarah M. Nakimuli, Annettee Kiwanuka, Noah Byamugisha, Josaphat Moffett, Ashley Aiken, Catherine E. |
author_facet | Namagembe, Imelda Chukwuma, Sarah M. Nakimuli, Annettee Kiwanuka, Noah Byamugisha, Josaphat Moffett, Ashley Aiken, Catherine E. |
author_sort | Namagembe, Imelda |
collection | PubMed |
description | BACKGROUND: Maternal deaths from uterine rupture continue to occur globally, with particularly high rates in sub-Saharan Africa. Maternal death reviews have been shown to be an effective part of cohesive strategies to prevent future deaths. OBJECTIVE: This study aimed to conduct maternal death reviews for all deaths following uterine rupture in the study center, to assess preventability, and to synthesize key learning points that may help to prevent future maternal deaths following uterine rupture. STUDY DESIGN: Thorough case reviews of all maternal deaths from 2016 to 2018 at the study center (a national referral hospital in urban Uganda) were conducted by trained multidisciplinary panels of obstetricians and midwives. Medical records of women who died following uterine rupture (n=37, 10.6% of all maternal deaths) were extracted for further analysis. RESULTS: Most maternal deaths due to uterine rupture (36/37, 97%) were preventable, with most having been still potentially preventable after the women reached the study center (24/36, 67%). Obstructed labor was the leading cause of uterine rupture, accounting for 73% (27/37) of cases. Previous cesarean delivery was confirmed in 38% (14/37) of cases. The incidence of grand multiparity was 11% (4/37), and 11% (4/37) were primiparous. Most women (28/37, 76%) died within 24 hours of admission. On arrival at the study center, 19 (51%) were critically ill. Exploratory laparotomy was performed in 54% (20/37) of cases, and a further 35% (13/37) died while awaiting laparotomy. Four women died shortly after arrival at the study center (within 1 hour) and received basic resuscitative treatment; 27% (10/37) of women who died had received antenatal planning or preparation. CONCLUSION: Most deaths due to uterine rupture were preventable. The key lessons that emerged from the reviews were: (1) careful birth preparation and complication awareness for women with known risk factors, (2) early recognition of obstructed labor, (3) close monitoring of obstetrical interventions known to be associated with uterine rupture, and (4) treating incipient or suspected uterine rupture as a time-critical obstetrical emergency. The recommendations emerging from our narrative reviews are suitable for implementation in low-resource obstetrical settings, where high numbers of deaths involving uterine rupture occur. |
format | Online Article Text |
id | pubmed-9563662 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-95636622022-10-21 Learning from maternal deaths due to uterine rupture: review of cases from peri-urban Uganda Namagembe, Imelda Chukwuma, Sarah M. Nakimuli, Annettee Kiwanuka, Noah Byamugisha, Josaphat Moffett, Ashley Aiken, Catherine E. AJOG Glob Rep Original Research BACKGROUND: Maternal deaths from uterine rupture continue to occur globally, with particularly high rates in sub-Saharan Africa. Maternal death reviews have been shown to be an effective part of cohesive strategies to prevent future deaths. OBJECTIVE: This study aimed to conduct maternal death reviews for all deaths following uterine rupture in the study center, to assess preventability, and to synthesize key learning points that may help to prevent future maternal deaths following uterine rupture. STUDY DESIGN: Thorough case reviews of all maternal deaths from 2016 to 2018 at the study center (a national referral hospital in urban Uganda) were conducted by trained multidisciplinary panels of obstetricians and midwives. Medical records of women who died following uterine rupture (n=37, 10.6% of all maternal deaths) were extracted for further analysis. RESULTS: Most maternal deaths due to uterine rupture (36/37, 97%) were preventable, with most having been still potentially preventable after the women reached the study center (24/36, 67%). Obstructed labor was the leading cause of uterine rupture, accounting for 73% (27/37) of cases. Previous cesarean delivery was confirmed in 38% (14/37) of cases. The incidence of grand multiparity was 11% (4/37), and 11% (4/37) were primiparous. Most women (28/37, 76%) died within 24 hours of admission. On arrival at the study center, 19 (51%) were critically ill. Exploratory laparotomy was performed in 54% (20/37) of cases, and a further 35% (13/37) died while awaiting laparotomy. Four women died shortly after arrival at the study center (within 1 hour) and received basic resuscitative treatment; 27% (10/37) of women who died had received antenatal planning or preparation. CONCLUSION: Most deaths due to uterine rupture were preventable. The key lessons that emerged from the reviews were: (1) careful birth preparation and complication awareness for women with known risk factors, (2) early recognition of obstructed labor, (3) close monitoring of obstetrical interventions known to be associated with uterine rupture, and (4) treating incipient or suspected uterine rupture as a time-critical obstetrical emergency. The recommendations emerging from our narrative reviews are suitable for implementation in low-resource obstetrical settings, where high numbers of deaths involving uterine rupture occur. Elsevier 2022-06-11 /pmc/articles/PMC9563662/ /pubmed/36276797 http://dx.doi.org/10.1016/j.xagr.2022.100063 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Original Research Namagembe, Imelda Chukwuma, Sarah M. Nakimuli, Annettee Kiwanuka, Noah Byamugisha, Josaphat Moffett, Ashley Aiken, Catherine E. Learning from maternal deaths due to uterine rupture: review of cases from peri-urban Uganda |
title | Learning from maternal deaths due to uterine rupture: review of cases from peri-urban Uganda |
title_full | Learning from maternal deaths due to uterine rupture: review of cases from peri-urban Uganda |
title_fullStr | Learning from maternal deaths due to uterine rupture: review of cases from peri-urban Uganda |
title_full_unstemmed | Learning from maternal deaths due to uterine rupture: review of cases from peri-urban Uganda |
title_short | Learning from maternal deaths due to uterine rupture: review of cases from peri-urban Uganda |
title_sort | learning from maternal deaths due to uterine rupture: review of cases from peri-urban uganda |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563662/ https://www.ncbi.nlm.nih.gov/pubmed/36276797 http://dx.doi.org/10.1016/j.xagr.2022.100063 |
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