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Adverse childhood experience referring to parental relationship is associated with the risk of alcohol dependence and with COMT Val158Met polymorphism, but out of gene-environment interactions
INTRODUCTION: Gene-environment interactions (GxE) are considered to make a substantial impact on the risk of alcohol dependence (AD). OBJECTIVES: The aim of the study: to test the associations between the functional polymorphism Val158Met (rs6265) in the catechol-O-methyl transferase (COMT) gene, af...
Autores principales: | Merkulova, T., Chuprova, N., Solovieva, M., Nikolishin, A., Kibitov, A., Grechany, S., Baranok, N., Rybakova, K., Soldatkin, V., Yakovlev, A., Trusova, A., Ponizovsky, P., Krupitsky, E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563675/ http://dx.doi.org/10.1192/j.eurpsy.2022.348 |
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