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Linearized teixobactin is inactive and after sequence enhancement, kills methicillin‐resistant Staphylococcus aureus via a different mechanism

Staphylococcus aureus (S. aureus) is a highly adaptable pathogen that can rapidly develop resistance to conventional antibiotics such as penicillin. Recently, teixobactin was discovered from uncultivated soil bacteria by using the i‐chip technology. This depsipeptide forms an ester bond between the...

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Detalles Bibliográficos
Autores principales: Wu, Qianhui, Mishra, Biswajit, Wang, Guangshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564113/
https://www.ncbi.nlm.nih.gov/pubmed/36249542
http://dx.doi.org/10.1002/pep2.24269