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Global Transcriptional and Epigenetic Reconfiguration during Chemical Reprogramming of Human Retinal Pigment Epithelial Cells into Photoreceptor-like Cells

Retinal degenerative diseases are frequently caused by the loss of retinal neural cells such as photoreceptors. Cell replacement is regarded as one of the most promising therapies. Multiple types of stem and somatic cells have been tested for photoreceptor conversion. However, current induction effi...

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Detalles Bibliográficos
Autores principales:	Deng, Xiaoqian, Lee, Ryan, Lim, Sin Yee, Zhong, Zheng, Wang, Jing, Liu, Yizhi, Fan, Guoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564162/ https://www.ncbi.nlm.nih.gov/pubmed/36231108 http://dx.doi.org/10.3390/cells11193146

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