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Structural Basis of β2 Integrin Inside—Out Activation

β2 integrins are expressed on all leukocytes. Precise regulation of the β2 integrin is critical for leukocyte adhesion and trafficking. In neutrophils, β2 integrins participate in slow rolling. When activated by inside–out signaling, fully activated β2 integrins mediate rapid leukocyte arrest and ad...

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Detalles Bibliográficos
Autores principales: Wen, Lai, Lyu, Qingkang, Ley, Klaus, Goult, Benjamin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564206/
https://www.ncbi.nlm.nih.gov/pubmed/36231001
http://dx.doi.org/10.3390/cells11193039

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