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Emergence of MUC1 in Mammals for Adaptation of Barrier Epithelia

SIMPLE SUMMARY: The evidence reviewed here indicates that MUC1-C evolved in mammals to promote inflammatory adaptation in barrier tissues that extends to resident stem cells and immune cells. Inflammatory memory is an essential process that protects barrier niches against future insults. Evolutionar...

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Detalles Bibliográficos
Autor principal: Kufe, Donald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564314/
https://www.ncbi.nlm.nih.gov/pubmed/36230728
http://dx.doi.org/10.3390/cancers14194805