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Moderate, Little, or No Improvements in Neurobehavioral Symptoms among Individuals with Long COVID: A 34-Country Retrospective Study

(1) Background: Some people with COVID-19 develop a series of symptoms that last for several months after infection, known as Long COVID. Although these symptoms interfere with people’s daily functioning and quality of life, few studies have focused on neurobehavioral symptoms and the risk factors a...

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Autores principales: Ramos-Usuga, Daniela, Perrin, Paul B., Bogdanova, Yelena, Olabarrieta-Landa, Laiene, Alzueta, Elisabet, Baker, Fiona C., Iacovides, Stella, Cortes, Mar, Arango-Lasprilla, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564784/
https://www.ncbi.nlm.nih.gov/pubmed/36231893
http://dx.doi.org/10.3390/ijerph191912593
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author Ramos-Usuga, Daniela
Perrin, Paul B.
Bogdanova, Yelena
Olabarrieta-Landa, Laiene
Alzueta, Elisabet
Baker, Fiona C.
Iacovides, Stella
Cortes, Mar
Arango-Lasprilla, Juan Carlos
author_facet Ramos-Usuga, Daniela
Perrin, Paul B.
Bogdanova, Yelena
Olabarrieta-Landa, Laiene
Alzueta, Elisabet
Baker, Fiona C.
Iacovides, Stella
Cortes, Mar
Arango-Lasprilla, Juan Carlos
author_sort Ramos-Usuga, Daniela
collection PubMed
description (1) Background: Some people with COVID-19 develop a series of symptoms that last for several months after infection, known as Long COVID. Although these symptoms interfere with people’s daily functioning and quality of life, few studies have focused on neurobehavioral symptoms and the risk factors associated with their development; (2) Methods: 1001 adults from 34 countries who had previously tested positive for COVID-19 completed the Neurobehavioral Symptom Inventory reporting the symptoms before their COVID-19 diagnosis, during the COVID-19 infection, and currently; (3) Results: Participants reported large-sized increases before vs. during COVID-19 in all domains. Participants reported a medium-sized improvement (during COVID-19 vs. now) in somatic symptoms, a small-sized improvement in affective symptoms, and very minor/no improvement in cognitive symptoms. The risk factors for increased neurobehavioral symptoms were: being female/trans, unemployed, younger age, low education, having another chronic health condition, greater COVID-19 severity, greater number of days since the COVID-19 diagnosis, not having received oxygen therapy, and having been hospitalized. Additionally, participants from North America, Europe, and Central Asia reported higher levels of symptoms across all domains relative to Latin America and Sub-Saharan Africa; (4) Conclusions: The results highlight the importance of evaluating and treating neurobehavioral symptoms after COVID-19, especially targeting the higher-risk groups identified. General rehabilitation strategies and evidence-based cognitive rehabilitation are needed in both the acute and Long COVID phases.
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spelling pubmed-95647842022-10-15 Moderate, Little, or No Improvements in Neurobehavioral Symptoms among Individuals with Long COVID: A 34-Country Retrospective Study Ramos-Usuga, Daniela Perrin, Paul B. Bogdanova, Yelena Olabarrieta-Landa, Laiene Alzueta, Elisabet Baker, Fiona C. Iacovides, Stella Cortes, Mar Arango-Lasprilla, Juan Carlos Int J Environ Res Public Health Article (1) Background: Some people with COVID-19 develop a series of symptoms that last for several months after infection, known as Long COVID. Although these symptoms interfere with people’s daily functioning and quality of life, few studies have focused on neurobehavioral symptoms and the risk factors associated with their development; (2) Methods: 1001 adults from 34 countries who had previously tested positive for COVID-19 completed the Neurobehavioral Symptom Inventory reporting the symptoms before their COVID-19 diagnosis, during the COVID-19 infection, and currently; (3) Results: Participants reported large-sized increases before vs. during COVID-19 in all domains. Participants reported a medium-sized improvement (during COVID-19 vs. now) in somatic symptoms, a small-sized improvement in affective symptoms, and very minor/no improvement in cognitive symptoms. The risk factors for increased neurobehavioral symptoms were: being female/trans, unemployed, younger age, low education, having another chronic health condition, greater COVID-19 severity, greater number of days since the COVID-19 diagnosis, not having received oxygen therapy, and having been hospitalized. Additionally, participants from North America, Europe, and Central Asia reported higher levels of symptoms across all domains relative to Latin America and Sub-Saharan Africa; (4) Conclusions: The results highlight the importance of evaluating and treating neurobehavioral symptoms after COVID-19, especially targeting the higher-risk groups identified. General rehabilitation strategies and evidence-based cognitive rehabilitation are needed in both the acute and Long COVID phases. MDPI 2022-10-02 /pmc/articles/PMC9564784/ /pubmed/36231893 http://dx.doi.org/10.3390/ijerph191912593 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ramos-Usuga, Daniela
Perrin, Paul B.
Bogdanova, Yelena
Olabarrieta-Landa, Laiene
Alzueta, Elisabet
Baker, Fiona C.
Iacovides, Stella
Cortes, Mar
Arango-Lasprilla, Juan Carlos
Moderate, Little, or No Improvements in Neurobehavioral Symptoms among Individuals with Long COVID: A 34-Country Retrospective Study
title Moderate, Little, or No Improvements in Neurobehavioral Symptoms among Individuals with Long COVID: A 34-Country Retrospective Study
title_full Moderate, Little, or No Improvements in Neurobehavioral Symptoms among Individuals with Long COVID: A 34-Country Retrospective Study
title_fullStr Moderate, Little, or No Improvements in Neurobehavioral Symptoms among Individuals with Long COVID: A 34-Country Retrospective Study
title_full_unstemmed Moderate, Little, or No Improvements in Neurobehavioral Symptoms among Individuals with Long COVID: A 34-Country Retrospective Study
title_short Moderate, Little, or No Improvements in Neurobehavioral Symptoms among Individuals with Long COVID: A 34-Country Retrospective Study
title_sort moderate, little, or no improvements in neurobehavioral symptoms among individuals with long covid: a 34-country retrospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564784/
https://www.ncbi.nlm.nih.gov/pubmed/36231893
http://dx.doi.org/10.3390/ijerph191912593
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