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The conductance and organization of the TMC1-containing mechanotransducer channel complex in auditory hair cells

Transmembrane channel-like protein 1 (TMC1) is thought to form the ion-conducting pore of the mechanoelectrical transducer (MET) channel in auditory hair cells. Using single-channel analysis and ionic permeability measurements, we characterized six missense mutations in the purported pore region of...

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Detalles Bibliográficos
Autores principales: Fettiplace, Robert, Furness, David N., Beurg, Maryline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564823/
https://www.ncbi.nlm.nih.gov/pubmed/36191207
http://dx.doi.org/10.1073/pnas.2210849119