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The conductance and organization of the TMC1-containing mechanotransducer channel complex in auditory hair cells
Transmembrane channel-like protein 1 (TMC1) is thought to form the ion-conducting pore of the mechanoelectrical transducer (MET) channel in auditory hair cells. Using single-channel analysis and ionic permeability measurements, we characterized six missense mutations in the purported pore region of...
Autores principales: | Fettiplace, Robert, Furness, David N., Beurg, Maryline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564823/ https://www.ncbi.nlm.nih.gov/pubmed/36191207 http://dx.doi.org/10.1073/pnas.2210849119 |
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