Cargando…

Neurodegenerative Diseases: Implications of Environmental and Climatic Influences on Neurotransmitters and Neuronal Hormones Activities

Neurodegenerative and neuronal-related diseases are major public health concerns. Human vulnerability to neurodegenerative diseases (NDDs) increases with age. Neuronal hormones and neurotransmitters are major determinant factors regulating brain structure and functions. The implications of environme...

Descripción completa

Detalles Bibliográficos
Autores principales: Ayeni, Emmanuel A., Aldossary, Ahmad M., Ayejoto, Daniel A., Gbadegesin, Lanre A., Alshehri, Abdullah A., Alfassam, Haya A., Afewerky, Henok K., Almughem, Fahad A., Bello, Saidu M., Tawfik, Essam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564880/
https://www.ncbi.nlm.nih.gov/pubmed/36231792
http://dx.doi.org/10.3390/ijerph191912495
_version_ 1784808756404551680
author Ayeni, Emmanuel A.
Aldossary, Ahmad M.
Ayejoto, Daniel A.
Gbadegesin, Lanre A.
Alshehri, Abdullah A.
Alfassam, Haya A.
Afewerky, Henok K.
Almughem, Fahad A.
Bello, Saidu M.
Tawfik, Essam A.
author_facet Ayeni, Emmanuel A.
Aldossary, Ahmad M.
Ayejoto, Daniel A.
Gbadegesin, Lanre A.
Alshehri, Abdullah A.
Alfassam, Haya A.
Afewerky, Henok K.
Almughem, Fahad A.
Bello, Saidu M.
Tawfik, Essam A.
author_sort Ayeni, Emmanuel A.
collection PubMed
description Neurodegenerative and neuronal-related diseases are major public health concerns. Human vulnerability to neurodegenerative diseases (NDDs) increases with age. Neuronal hormones and neurotransmitters are major determinant factors regulating brain structure and functions. The implications of environmental and climatic changes emerged recently as influence factors on numerous diseases. However, the complex interaction of neurotransmitters and neuronal hormones and their depletion under environmental and climatic influences on NDDs are not well established in the literature. In this review, we aim to explore the connection between the environmental and climatic factors to NDDs and to highlight the available and potential therapeutic interventions that could use to improve the quality of life and reduce susceptibility to NDDs.
format Online
Article
Text
id pubmed-9564880
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-95648802022-10-15 Neurodegenerative Diseases: Implications of Environmental and Climatic Influences on Neurotransmitters and Neuronal Hormones Activities Ayeni, Emmanuel A. Aldossary, Ahmad M. Ayejoto, Daniel A. Gbadegesin, Lanre A. Alshehri, Abdullah A. Alfassam, Haya A. Afewerky, Henok K. Almughem, Fahad A. Bello, Saidu M. Tawfik, Essam A. Int J Environ Res Public Health Review Neurodegenerative and neuronal-related diseases are major public health concerns. Human vulnerability to neurodegenerative diseases (NDDs) increases with age. Neuronal hormones and neurotransmitters are major determinant factors regulating brain structure and functions. The implications of environmental and climatic changes emerged recently as influence factors on numerous diseases. However, the complex interaction of neurotransmitters and neuronal hormones and their depletion under environmental and climatic influences on NDDs are not well established in the literature. In this review, we aim to explore the connection between the environmental and climatic factors to NDDs and to highlight the available and potential therapeutic interventions that could use to improve the quality of life and reduce susceptibility to NDDs. MDPI 2022-09-30 /pmc/articles/PMC9564880/ /pubmed/36231792 http://dx.doi.org/10.3390/ijerph191912495 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ayeni, Emmanuel A.
Aldossary, Ahmad M.
Ayejoto, Daniel A.
Gbadegesin, Lanre A.
Alshehri, Abdullah A.
Alfassam, Haya A.
Afewerky, Henok K.
Almughem, Fahad A.
Bello, Saidu M.
Tawfik, Essam A.
Neurodegenerative Diseases: Implications of Environmental and Climatic Influences on Neurotransmitters and Neuronal Hormones Activities
title Neurodegenerative Diseases: Implications of Environmental and Climatic Influences on Neurotransmitters and Neuronal Hormones Activities
title_full Neurodegenerative Diseases: Implications of Environmental and Climatic Influences on Neurotransmitters and Neuronal Hormones Activities
title_fullStr Neurodegenerative Diseases: Implications of Environmental and Climatic Influences on Neurotransmitters and Neuronal Hormones Activities
title_full_unstemmed Neurodegenerative Diseases: Implications of Environmental and Climatic Influences on Neurotransmitters and Neuronal Hormones Activities
title_short Neurodegenerative Diseases: Implications of Environmental and Climatic Influences on Neurotransmitters and Neuronal Hormones Activities
title_sort neurodegenerative diseases: implications of environmental and climatic influences on neurotransmitters and neuronal hormones activities
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564880/
https://www.ncbi.nlm.nih.gov/pubmed/36231792
http://dx.doi.org/10.3390/ijerph191912495
work_keys_str_mv AT ayeniemmanuela neurodegenerativediseasesimplicationsofenvironmentalandclimaticinfluencesonneurotransmittersandneuronalhormonesactivities
AT aldossaryahmadm neurodegenerativediseasesimplicationsofenvironmentalandclimaticinfluencesonneurotransmittersandneuronalhormonesactivities
AT ayejotodaniela neurodegenerativediseasesimplicationsofenvironmentalandclimaticinfluencesonneurotransmittersandneuronalhormonesactivities
AT gbadegesinlanrea neurodegenerativediseasesimplicationsofenvironmentalandclimaticinfluencesonneurotransmittersandneuronalhormonesactivities
AT alshehriabdullaha neurodegenerativediseasesimplicationsofenvironmentalandclimaticinfluencesonneurotransmittersandneuronalhormonesactivities
AT alfassamhayaa neurodegenerativediseasesimplicationsofenvironmentalandclimaticinfluencesonneurotransmittersandneuronalhormonesactivities
AT afewerkyhenokk neurodegenerativediseasesimplicationsofenvironmentalandclimaticinfluencesonneurotransmittersandneuronalhormonesactivities
AT almughemfahada neurodegenerativediseasesimplicationsofenvironmentalandclimaticinfluencesonneurotransmittersandneuronalhormonesactivities
AT bellosaidum neurodegenerativediseasesimplicationsofenvironmentalandclimaticinfluencesonneurotransmittersandneuronalhormonesactivities
AT tawfikessama neurodegenerativediseasesimplicationsofenvironmentalandclimaticinfluencesonneurotransmittersandneuronalhormonesactivities