Sequestration of gut pathobionts in intraluminal casts, a mechanism to avoid dysregulated T cell activation by pathobionts

T cells that express the transcription factor RORγ, regulatory (Treg), or conventional (Th17) are strongly influenced by intestinal symbionts. In a genetic approach to identify mechanisms underlying this influence, we performed a screen for microbial genes implicated, in germfree mice monocolonized...

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Detalles Bibliográficos
Autores principales: Sassone-Corsi, Martina, Azriel, Shalhevet, Simon, Ariel, Ramanan, Deepshika, Ortiz-Lopez, Adriana, Chen, Felicia, Yissachar, Nissan, Mathis, Diane, Benoist, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565271/
https://www.ncbi.nlm.nih.gov/pubmed/36201539
http://dx.doi.org/10.1073/pnas.2209624119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565271/
https://www.ncbi.nlm.nih.gov/pubmed/36201539
http://dx.doi.org/10.1073/pnas.2209624119

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