Cargando…
The ubiquitous microtubule-associated protein 4 (MAP4) controls organelle distribution by regulating the activity of the kinesin motor
Regulation of organelle transport by molecular motors along the cytoskeletal microtubules is central to maintaining cellular functions. Here, we show that the ubiquitous tau-related microtubule-associated protein 4 (MAP4) can bias the bidirectional transport of organelles toward the microtubule minu...
Autores principales: | Nabti, Ibtissem, Reddy, Babu J. N., Rezgui, Rachid, Wang, Wenqi, Gross, Steven P., Shubeita, George T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565364/ https://www.ncbi.nlm.nih.gov/pubmed/36191197 http://dx.doi.org/10.1073/pnas.2206677119 |
Ejemplares similares
-
MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport
por: Tymanskyj, Stephen R, et al.
Publicado: (2018) -
The role of kinesin and other soluble factors in organelle movement along microtubules
Publicado: (1988) -
Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14
por: Hentrich, Christian, et al.
Publicado: (2010) -
Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding
por: Solon, April L., et al.
Publicado: (2021) -
Kinesin is bound with high affinity to squid axon organelles that move to the plus-end of microtubules
Publicado: (1992)