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SANReSP: A new Italian questionnaire to screen patients for obstructive sleep apnea

PURPOSE: Obstructive sleep apnea (OSA) is a common, prevalent, and underdiagnosed disorder. Its lack of diagnosis and treatment is associated with increased morbidity and mortality. Previous screening questionnaires investigated parameters including body mass index, age, neck circumference, and sex,...

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Autores principales: Romano, Salvatore, Lo Bue, Anna, Salvaggio, Adriana, Oliveira, Luis V. F., Ferini-Strambi, Luigi, Insalaco, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565397/
https://www.ncbi.nlm.nih.gov/pubmed/36240186
http://dx.doi.org/10.1371/journal.pone.0276217
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author Romano, Salvatore
Lo Bue, Anna
Salvaggio, Adriana
Oliveira, Luis V. F.
Ferini-Strambi, Luigi
Insalaco, Giuseppe
author_facet Romano, Salvatore
Lo Bue, Anna
Salvaggio, Adriana
Oliveira, Luis V. F.
Ferini-Strambi, Luigi
Insalaco, Giuseppe
author_sort Romano, Salvatore
collection PubMed
description PURPOSE: Obstructive sleep apnea (OSA) is a common, prevalent, and underdiagnosed disorder. Its lack of diagnosis and treatment is associated with increased morbidity and mortality. Previous screening questionnaires investigated parameters including body mass index, age, neck circumference, and sex, in addition to symptoms. This study aimed to validate a new Italian, self-administered, and easy-to-use six-item questionnaire that evaluates only subjective symptoms. PATIENTS AND METHODS: The present study included 2622 patients (male, 2011; female, 611). Patients who were at least 18 years old, spoke Italian, referred to our sleep clinic for possible OSA, and completed the self-administered SANReSP questionnaire were recruited for the study. The predictive performance of the questionnaire was also evaluated. RESULTS: Nocturnal study showed 89.9% of OSA patients had apnea-hypopnea index (AHI) ≥ 5/h; 68.7%, AHI ≥ 15/h; and 48.2%, AHI ≥ 30/h. The optimal SANReSP score for AHI ≥ 5/h was >3 with a sensitivity and specificity of 74.76% and 67.92%, respectively, and an area under receiver operating characteristic curve (ROC) of 0.76. For moderate–severe OSA, the optimal SANReSP score was >3 (sensitivity, 78.18%; specificity, 46.53%; ROC, 0.66). For severe OSA, the optimal SANReSP score was >4 (sensitivity, 59.10%; specificity, 64.73%; ROC, 0.65). The probability of OSA increased with higher SANReSP scores (98.7% and 97.9% in men and women, respectively). CONCLUSION: The SANReSP questionnaire is a short, easy-to-use, and self-administered screening tool for OSA. Its performance is similar to that of other widely used questionnaires; furthermore, it is advantageous in that it does not require anthropometric measurements.
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spelling pubmed-95653972022-10-15 SANReSP: A new Italian questionnaire to screen patients for obstructive sleep apnea Romano, Salvatore Lo Bue, Anna Salvaggio, Adriana Oliveira, Luis V. F. Ferini-Strambi, Luigi Insalaco, Giuseppe PLoS One Research Article PURPOSE: Obstructive sleep apnea (OSA) is a common, prevalent, and underdiagnosed disorder. Its lack of diagnosis and treatment is associated with increased morbidity and mortality. Previous screening questionnaires investigated parameters including body mass index, age, neck circumference, and sex, in addition to symptoms. This study aimed to validate a new Italian, self-administered, and easy-to-use six-item questionnaire that evaluates only subjective symptoms. PATIENTS AND METHODS: The present study included 2622 patients (male, 2011; female, 611). Patients who were at least 18 years old, spoke Italian, referred to our sleep clinic for possible OSA, and completed the self-administered SANReSP questionnaire were recruited for the study. The predictive performance of the questionnaire was also evaluated. RESULTS: Nocturnal study showed 89.9% of OSA patients had apnea-hypopnea index (AHI) ≥ 5/h; 68.7%, AHI ≥ 15/h; and 48.2%, AHI ≥ 30/h. The optimal SANReSP score for AHI ≥ 5/h was >3 with a sensitivity and specificity of 74.76% and 67.92%, respectively, and an area under receiver operating characteristic curve (ROC) of 0.76. For moderate–severe OSA, the optimal SANReSP score was >3 (sensitivity, 78.18%; specificity, 46.53%; ROC, 0.66). For severe OSA, the optimal SANReSP score was >4 (sensitivity, 59.10%; specificity, 64.73%; ROC, 0.65). The probability of OSA increased with higher SANReSP scores (98.7% and 97.9% in men and women, respectively). CONCLUSION: The SANReSP questionnaire is a short, easy-to-use, and self-administered screening tool for OSA. Its performance is similar to that of other widely used questionnaires; furthermore, it is advantageous in that it does not require anthropometric measurements. Public Library of Science 2022-10-14 /pmc/articles/PMC9565397/ /pubmed/36240186 http://dx.doi.org/10.1371/journal.pone.0276217 Text en © 2022 Romano et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Romano, Salvatore
Lo Bue, Anna
Salvaggio, Adriana
Oliveira, Luis V. F.
Ferini-Strambi, Luigi
Insalaco, Giuseppe
SANReSP: A new Italian questionnaire to screen patients for obstructive sleep apnea
title SANReSP: A new Italian questionnaire to screen patients for obstructive sleep apnea
title_full SANReSP: A new Italian questionnaire to screen patients for obstructive sleep apnea
title_fullStr SANReSP: A new Italian questionnaire to screen patients for obstructive sleep apnea
title_full_unstemmed SANReSP: A new Italian questionnaire to screen patients for obstructive sleep apnea
title_short SANReSP: A new Italian questionnaire to screen patients for obstructive sleep apnea
title_sort sanresp: a new italian questionnaire to screen patients for obstructive sleep apnea
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565397/
https://www.ncbi.nlm.nih.gov/pubmed/36240186
http://dx.doi.org/10.1371/journal.pone.0276217
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