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Pilot clinical and pharmacokinetic study of Δ(9)-Tetrahydrocannabinol (THC)/Cannabidiol (CBD) nanoparticle oro-buccal spray in patients with advanced cancer experiencing uncontrolled pain

This pilot study aimed to assess the safety, tolerability, pharmacokinetics and exploratory analgesic effect of a novel water-soluble oro-buccal nanoparticle spray of a cannabis-based medicine (MDCNS-01) in patients with advanced incurable malignancy with unrelieved pain from opioid analgesic. The s...

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Detalles Bibliográficos
Autores principales:	Clarke, Stephen, Butcher, Belinda E., McLachlan, Andrew J., Henson, Jeremy D., Rutolo, David, Hall, Sean, Vitetta, Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565400/ https://www.ncbi.nlm.nih.gov/pubmed/36240167 http://dx.doi.org/10.1371/journal.pone.0270543

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