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Personalized quantitative models of NAD metabolism in hepatocellular carcinoma identify a subgroup with poor prognosis

Cancer cells are known to undergo metabolic adaptation to cater to their enhanced energy demand. Nicotinamide adenine dinucleotide (NAD) is an essential metabolite regulating many cellular processes within the cell. The enzymes required for NAD synthesis, starting from the base precursor - tryptopha...

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Detalles Bibliográficos
Autores principales: Chedere, Adithya, Mishra, Madhulika, Kulkarni, Omkar, Sriraman, Shrisruti, Chandra, Nagasuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565660/
https://www.ncbi.nlm.nih.gov/pubmed/36249025
http://dx.doi.org/10.3389/fonc.2022.954512