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Sex Differences in Cardiovascular Disease Mortality in Brazil between 1996 and 2019

Background: cardiovascular diseases (CVD) are Brazil’s leading causes of death in women and men. This study analyzed age-adjusted death rate (DRaj) trends from all causes of death (ACD), CVD, ischemic heart disease (IHD), and stroke in women and men aged 35 to 74 years from 1996 to 2019. Methods: We...

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Autores principales: Mansur, Antonio de Padua, Favarato, Desidério, Strunz, Célia Maria Cassaro, Avakian, Solange Desirée, Pereira-Barretto, Antonio Carlos, Bocchi, Edimar Alcides, César, Luiz Antonio Machado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9566207/
https://www.ncbi.nlm.nih.gov/pubmed/36232126
http://dx.doi.org/10.3390/ijerph191912827
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author Mansur, Antonio de Padua
Favarato, Desidério
Strunz, Célia Maria Cassaro
Avakian, Solange Desirée
Pereira-Barretto, Antonio Carlos
Bocchi, Edimar Alcides
César, Luiz Antonio Machado
author_facet Mansur, Antonio de Padua
Favarato, Desidério
Strunz, Célia Maria Cassaro
Avakian, Solange Desirée
Pereira-Barretto, Antonio Carlos
Bocchi, Edimar Alcides
César, Luiz Antonio Machado
author_sort Mansur, Antonio de Padua
collection PubMed
description Background: cardiovascular diseases (CVD) are Brazil’s leading causes of death in women and men. This study analyzed age-adjusted death rate (DRaj) trends from all causes of death (ACD), CVD, ischemic heart disease (IHD), and stroke in women and men aged 35 to 74 years from 1996 to 2019. Methods: We analyzed DRaj trends for all causes of death (ACD), CVD, IHD, and stroke. Data were from the Ministry of Health mortality database. Joinpoint Regression Program™ performed trend analysis and adjustments in death rates. Average annual percentage change (AAPC) determined the intensity of changes. Results: In women, DRaj reduced for ACD (AAPC = −1.6%); CVD (AAPC = −2.6%); IHD (AAPC = −1.9%); and stroke (AAPC = −4.6%) (p < 0.001 for all). In men, ACD reduced from 1996 to 2004 (AAPC = −0.9%; p < 0.001), from 2012 to 2019 (AAPC = −1.9%; p < 0.001), and unchanged from 2004 to 2012; CVD (AAPC = −2.1%); IHD (AAPC = −1.5%); stroke (AAPC = −4.9%) (p < 0.001 for all) reduced from 1996 to 2019. From 1996 to 2019, the male/female ratio for ACD remained unchanged. CVD increased from 1.58 to 1.83, IHD from 1.99 to 2.30, and stroke from 1.52 to 1.83. Conclusion: ACD, CVD, IHD, and stroke were reduced more significantly in women, and the ratio of CVD, IHD, and CVD in men and women increased more in men. Future studies will be needed to determine the main factors responsible for a better outcome in women.
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spelling pubmed-95662072022-10-15 Sex Differences in Cardiovascular Disease Mortality in Brazil between 1996 and 2019 Mansur, Antonio de Padua Favarato, Desidério Strunz, Célia Maria Cassaro Avakian, Solange Desirée Pereira-Barretto, Antonio Carlos Bocchi, Edimar Alcides César, Luiz Antonio Machado Int J Environ Res Public Health Article Background: cardiovascular diseases (CVD) are Brazil’s leading causes of death in women and men. This study analyzed age-adjusted death rate (DRaj) trends from all causes of death (ACD), CVD, ischemic heart disease (IHD), and stroke in women and men aged 35 to 74 years from 1996 to 2019. Methods: We analyzed DRaj trends for all causes of death (ACD), CVD, IHD, and stroke. Data were from the Ministry of Health mortality database. Joinpoint Regression Program™ performed trend analysis and adjustments in death rates. Average annual percentage change (AAPC) determined the intensity of changes. Results: In women, DRaj reduced for ACD (AAPC = −1.6%); CVD (AAPC = −2.6%); IHD (AAPC = −1.9%); and stroke (AAPC = −4.6%) (p < 0.001 for all). In men, ACD reduced from 1996 to 2004 (AAPC = −0.9%; p < 0.001), from 2012 to 2019 (AAPC = −1.9%; p < 0.001), and unchanged from 2004 to 2012; CVD (AAPC = −2.1%); IHD (AAPC = −1.5%); stroke (AAPC = −4.9%) (p < 0.001 for all) reduced from 1996 to 2019. From 1996 to 2019, the male/female ratio for ACD remained unchanged. CVD increased from 1.58 to 1.83, IHD from 1.99 to 2.30, and stroke from 1.52 to 1.83. Conclusion: ACD, CVD, IHD, and stroke were reduced more significantly in women, and the ratio of CVD, IHD, and CVD in men and women increased more in men. Future studies will be needed to determine the main factors responsible for a better outcome in women. MDPI 2022-10-07 /pmc/articles/PMC9566207/ /pubmed/36232126 http://dx.doi.org/10.3390/ijerph191912827 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mansur, Antonio de Padua
Favarato, Desidério
Strunz, Célia Maria Cassaro
Avakian, Solange Desirée
Pereira-Barretto, Antonio Carlos
Bocchi, Edimar Alcides
César, Luiz Antonio Machado
Sex Differences in Cardiovascular Disease Mortality in Brazil between 1996 and 2019
title Sex Differences in Cardiovascular Disease Mortality in Brazil between 1996 and 2019
title_full Sex Differences in Cardiovascular Disease Mortality in Brazil between 1996 and 2019
title_fullStr Sex Differences in Cardiovascular Disease Mortality in Brazil between 1996 and 2019
title_full_unstemmed Sex Differences in Cardiovascular Disease Mortality in Brazil between 1996 and 2019
title_short Sex Differences in Cardiovascular Disease Mortality in Brazil between 1996 and 2019
title_sort sex differences in cardiovascular disease mortality in brazil between 1996 and 2019
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9566207/
https://www.ncbi.nlm.nih.gov/pubmed/36232126
http://dx.doi.org/10.3390/ijerph191912827
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