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New Onset Cardiac Murmur and Exertional Dyspnea in an Apparently Healthy Child: A Rare Localization of Obstructive Myxoma in the Right Ventricle Outflow Tract without Pulmonary Embolization—A Case Report and Literature Review

Myxomas are slowly growing benign neoplasms which are rare in children. Up to 80% can be located in the left atrium and generate symptoms such as embolism, cardiac failure, fever and weight loss. Rarely, myxomas can be detected in the right ventricle outflow tract, causing arrhythmias, pulmonary emb...

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Autores principales: D’Anna, Carolina, Villani, Alberto, Ammirati, Antonio, Francalanci, Paola, Ragni, Laura, Cecconi, Giulia, Secinaro, Aurelio, Chinali, Marcello, Santilli, Antonella, Guccione, Paolo, Galletti, Lorenzo, Brancaccio, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9566503/
https://www.ncbi.nlm.nih.gov/pubmed/36232202
http://dx.doi.org/10.3390/ijerph191912888
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author D’Anna, Carolina
Villani, Alberto
Ammirati, Antonio
Francalanci, Paola
Ragni, Laura
Cecconi, Giulia
Secinaro, Aurelio
Chinali, Marcello
Santilli, Antonella
Guccione, Paolo
Galletti, Lorenzo
Brancaccio, Gianluca
author_facet D’Anna, Carolina
Villani, Alberto
Ammirati, Antonio
Francalanci, Paola
Ragni, Laura
Cecconi, Giulia
Secinaro, Aurelio
Chinali, Marcello
Santilli, Antonella
Guccione, Paolo
Galletti, Lorenzo
Brancaccio, Gianluca
author_sort D’Anna, Carolina
collection PubMed
description Myxomas are slowly growing benign neoplasms which are rare in children. Up to 80% can be located in the left atrium and generate symptoms such as embolism, cardiac failure, fever and weight loss. Rarely, myxomas can be detected in the right ventricle outflow tract, causing arrhythmias, pulmonary emboli and sudden death. We report the case of a 13-year-old healthy child brought to the Emergency Department (ED) of the Children’s Hospital Bambino Gesù, Rome, for recent dyspnea, chest pain on exertion and new onset cardiac murmur. Patient underwent medical examination and echocardiogram with the finding of a rounded and lobulated voluminous mass in the right ventricle outflow tract (RVOT) which caused severe obstruction. The contrast computed tomography (CT) scan confirmed the presence of a heterogeneously enhancing soft-tissue mass occupying the RVOT with no evidence of pulmonary embolization. The mass was surgically excised, and the pathologic examination confirmed our suspicion of myxoma. Our experience suggests that myxoma can have mild clinical symptoms, the presentation may be non-specific, and diagnosis can be a challenge Careful examination and a diagnostic imaging workup, primarily with the transthoracic echocardiogram, are needful to make a rapid differential diagnosis and to better manage surgical treatment and follow-up.
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spelling pubmed-95665032022-10-15 New Onset Cardiac Murmur and Exertional Dyspnea in an Apparently Healthy Child: A Rare Localization of Obstructive Myxoma in the Right Ventricle Outflow Tract without Pulmonary Embolization—A Case Report and Literature Review D’Anna, Carolina Villani, Alberto Ammirati, Antonio Francalanci, Paola Ragni, Laura Cecconi, Giulia Secinaro, Aurelio Chinali, Marcello Santilli, Antonella Guccione, Paolo Galletti, Lorenzo Brancaccio, Gianluca Int J Environ Res Public Health Case Report Myxomas are slowly growing benign neoplasms which are rare in children. Up to 80% can be located in the left atrium and generate symptoms such as embolism, cardiac failure, fever and weight loss. Rarely, myxomas can be detected in the right ventricle outflow tract, causing arrhythmias, pulmonary emboli and sudden death. We report the case of a 13-year-old healthy child brought to the Emergency Department (ED) of the Children’s Hospital Bambino Gesù, Rome, for recent dyspnea, chest pain on exertion and new onset cardiac murmur. Patient underwent medical examination and echocardiogram with the finding of a rounded and lobulated voluminous mass in the right ventricle outflow tract (RVOT) which caused severe obstruction. The contrast computed tomography (CT) scan confirmed the presence of a heterogeneously enhancing soft-tissue mass occupying the RVOT with no evidence of pulmonary embolization. The mass was surgically excised, and the pathologic examination confirmed our suspicion of myxoma. Our experience suggests that myxoma can have mild clinical symptoms, the presentation may be non-specific, and diagnosis can be a challenge Careful examination and a diagnostic imaging workup, primarily with the transthoracic echocardiogram, are needful to make a rapid differential diagnosis and to better manage surgical treatment and follow-up. MDPI 2022-10-08 /pmc/articles/PMC9566503/ /pubmed/36232202 http://dx.doi.org/10.3390/ijerph191912888 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
D’Anna, Carolina
Villani, Alberto
Ammirati, Antonio
Francalanci, Paola
Ragni, Laura
Cecconi, Giulia
Secinaro, Aurelio
Chinali, Marcello
Santilli, Antonella
Guccione, Paolo
Galletti, Lorenzo
Brancaccio, Gianluca
New Onset Cardiac Murmur and Exertional Dyspnea in an Apparently Healthy Child: A Rare Localization of Obstructive Myxoma in the Right Ventricle Outflow Tract without Pulmonary Embolization—A Case Report and Literature Review
title New Onset Cardiac Murmur and Exertional Dyspnea in an Apparently Healthy Child: A Rare Localization of Obstructive Myxoma in the Right Ventricle Outflow Tract without Pulmonary Embolization—A Case Report and Literature Review
title_full New Onset Cardiac Murmur and Exertional Dyspnea in an Apparently Healthy Child: A Rare Localization of Obstructive Myxoma in the Right Ventricle Outflow Tract without Pulmonary Embolization—A Case Report and Literature Review
title_fullStr New Onset Cardiac Murmur and Exertional Dyspnea in an Apparently Healthy Child: A Rare Localization of Obstructive Myxoma in the Right Ventricle Outflow Tract without Pulmonary Embolization—A Case Report and Literature Review
title_full_unstemmed New Onset Cardiac Murmur and Exertional Dyspnea in an Apparently Healthy Child: A Rare Localization of Obstructive Myxoma in the Right Ventricle Outflow Tract without Pulmonary Embolization—A Case Report and Literature Review
title_short New Onset Cardiac Murmur and Exertional Dyspnea in an Apparently Healthy Child: A Rare Localization of Obstructive Myxoma in the Right Ventricle Outflow Tract without Pulmonary Embolization—A Case Report and Literature Review
title_sort new onset cardiac murmur and exertional dyspnea in an apparently healthy child: a rare localization of obstructive myxoma in the right ventricle outflow tract without pulmonary embolization—a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9566503/
https://www.ncbi.nlm.nih.gov/pubmed/36232202
http://dx.doi.org/10.3390/ijerph191912888
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