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Antibiotic-Resistant Bacteria in Drinking Water from the Greater Accra Region, Ghana: A Cross-Sectional Study, December 2021–March 2022
With safely managed water accessible to only 19% of the population in Ghana, the majority of its residents are at risk of drinking contaminated water. Furthermore, this water could be a potential vehicle for the transmission of antimicrobial-resistant bacteria. This study assessed the presence of ba...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9566567/ https://www.ncbi.nlm.nih.gov/pubmed/36231603 http://dx.doi.org/10.3390/ijerph191912300 |
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author | Ahmed, Hawa Zolfo, Maria Williams, Anita Ashubwe-Jalemba, Jacklyne Tweya, Hannock Adeapena, Wisdom Labi, Appiah-Korang Adomako, Lady A. B. Addico, Gloria N. D. Banu, Regina A. Akrong, Mark O. Quarcoo, Gerard Borbor, Selorm Osei-Atweneboana, Mike Y. |
author_facet | Ahmed, Hawa Zolfo, Maria Williams, Anita Ashubwe-Jalemba, Jacklyne Tweya, Hannock Adeapena, Wisdom Labi, Appiah-Korang Adomako, Lady A. B. Addico, Gloria N. D. Banu, Regina A. Akrong, Mark O. Quarcoo, Gerard Borbor, Selorm Osei-Atweneboana, Mike Y. |
author_sort | Ahmed, Hawa |
collection | PubMed |
description | With safely managed water accessible to only 19% of the population in Ghana, the majority of its residents are at risk of drinking contaminated water. Furthermore, this water could be a potential vehicle for the transmission of antimicrobial-resistant bacteria. This study assessed the presence of bacteria and the antibiotic resistance profile of Escherichia coli and Pseudomonas aeruginosa in drinking-water sources using membrane filtration and Kirby–Bauer disc diffusion methods. A total of 524 water samples were analyzed for total coliforms, total heterotrophic bacteria, E. coli and P. aeruginosa. Samples included sachets, bottled water, tap water, borehole and well water. Most of the sachet and bottled water samples were within the limits of Ghana’s standards for safe drinking water for the parameters tested. Over 50% of tap and borehole water was also free of E. coli and P. aeruginosa. Overall, of 115 E. coli isolates from tap and ground water samples, most were resistant to cefuroxime (88.7%), trimethoprim–sulfamethoxazole (62.6%) and amoxicillin–clavulanate (52.2%). P. aeruginosa isolates were most resistant to aztreonam (48%). Multidrug resistance was predominantly seen among E. coli isolates (58%). Evidence from this study calls for routine antimicrobial resistance surveillance in drinking water across the country and additional treatment of water sources at household levels. |
format | Online Article Text |
id | pubmed-9566567 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95665672022-10-15 Antibiotic-Resistant Bacteria in Drinking Water from the Greater Accra Region, Ghana: A Cross-Sectional Study, December 2021–March 2022 Ahmed, Hawa Zolfo, Maria Williams, Anita Ashubwe-Jalemba, Jacklyne Tweya, Hannock Adeapena, Wisdom Labi, Appiah-Korang Adomako, Lady A. B. Addico, Gloria N. D. Banu, Regina A. Akrong, Mark O. Quarcoo, Gerard Borbor, Selorm Osei-Atweneboana, Mike Y. Int J Environ Res Public Health Article With safely managed water accessible to only 19% of the population in Ghana, the majority of its residents are at risk of drinking contaminated water. Furthermore, this water could be a potential vehicle for the transmission of antimicrobial-resistant bacteria. This study assessed the presence of bacteria and the antibiotic resistance profile of Escherichia coli and Pseudomonas aeruginosa in drinking-water sources using membrane filtration and Kirby–Bauer disc diffusion methods. A total of 524 water samples were analyzed for total coliforms, total heterotrophic bacteria, E. coli and P. aeruginosa. Samples included sachets, bottled water, tap water, borehole and well water. Most of the sachet and bottled water samples were within the limits of Ghana’s standards for safe drinking water for the parameters tested. Over 50% of tap and borehole water was also free of E. coli and P. aeruginosa. Overall, of 115 E. coli isolates from tap and ground water samples, most were resistant to cefuroxime (88.7%), trimethoprim–sulfamethoxazole (62.6%) and amoxicillin–clavulanate (52.2%). P. aeruginosa isolates were most resistant to aztreonam (48%). Multidrug resistance was predominantly seen among E. coli isolates (58%). Evidence from this study calls for routine antimicrobial resistance surveillance in drinking water across the country and additional treatment of water sources at household levels. MDPI 2022-09-28 /pmc/articles/PMC9566567/ /pubmed/36231603 http://dx.doi.org/10.3390/ijerph191912300 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ahmed, Hawa Zolfo, Maria Williams, Anita Ashubwe-Jalemba, Jacklyne Tweya, Hannock Adeapena, Wisdom Labi, Appiah-Korang Adomako, Lady A. B. Addico, Gloria N. D. Banu, Regina A. Akrong, Mark O. Quarcoo, Gerard Borbor, Selorm Osei-Atweneboana, Mike Y. Antibiotic-Resistant Bacteria in Drinking Water from the Greater Accra Region, Ghana: A Cross-Sectional Study, December 2021–March 2022 |
title | Antibiotic-Resistant Bacteria in Drinking Water from the Greater Accra Region, Ghana: A Cross-Sectional Study, December 2021–March 2022 |
title_full | Antibiotic-Resistant Bacteria in Drinking Water from the Greater Accra Region, Ghana: A Cross-Sectional Study, December 2021–March 2022 |
title_fullStr | Antibiotic-Resistant Bacteria in Drinking Water from the Greater Accra Region, Ghana: A Cross-Sectional Study, December 2021–March 2022 |
title_full_unstemmed | Antibiotic-Resistant Bacteria in Drinking Water from the Greater Accra Region, Ghana: A Cross-Sectional Study, December 2021–March 2022 |
title_short | Antibiotic-Resistant Bacteria in Drinking Water from the Greater Accra Region, Ghana: A Cross-Sectional Study, December 2021–March 2022 |
title_sort | antibiotic-resistant bacteria in drinking water from the greater accra region, ghana: a cross-sectional study, december 2021–march 2022 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9566567/ https://www.ncbi.nlm.nih.gov/pubmed/36231603 http://dx.doi.org/10.3390/ijerph191912300 |
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