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The impact of constitutive mTORC1 hyperactivity on structural synaptic plasticity and social behaviour under standard conditions and environmental enrichment

INTRODUCTION: Autism spectrum disorders (ASD) are a group of neurodevelopmental disabilities causing major social, communication, and behavioural challenges. Although causative roles of altered genes and environment are recognized, the underlying mechanisms remain elusive. OBJECTIVES: We carried out...

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Detalles Bibliográficos
Autores principales: Granak, S., Tuckova, K., Kutna, V., Vojtechova, I., Bajkova, L., Petrasek, T., Ovsepian, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9566860/
http://dx.doi.org/10.1192/j.eurpsy.2022.506