IL-20RB mediates tumoral response to osteoclastic niches and promotes bone metastasis of lung cancer

Bone is a common site of metastasis in lung cancer, but the regulatory mechanism remains incompletely understood. Osteoclasts are known to play crucial roles in osteolytic bone metastasis by digesting bone matrix and indirectly enhancing tumor colonization. In this study, we found that IL receptor 2...

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Detalles Bibliográficos
Autores principales: He, Yunfei, Luo, Wenqian, Liu, Yingjie, Wang, Yuan, Ma, Chengxin, Wu, Qiuyao, Tian, Pu, He, Dasa, Jia, Zhenchang, Lv, Xianzhe, Ma, Yu-Shui, Yang, Haitang, Xu, Ke, Zhang, Xue, Xiao, Yansen, Zhang, Peiyuan, Liang, Yajun, Fu, Da, Yao, Feng, Hu, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9566910/
https://www.ncbi.nlm.nih.gov/pubmed/36006737
http://dx.doi.org/10.1172/JCI157917

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