Mast cell–derived factor XIIIA contributes to sexual dimorphic defense against group B streptococcal infections

Invasive bacterial infections remain a major cause of human morbidity. Group B streptococcus (GBS) are Gram-positive bacteria that cause invasive infections in humans. Here, we show that factor XIIIA–deficient (FXIIIA-deficient) female mice exhibited significantly increased susceptibility to GBS inf...

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Detalles Bibliográficos
Autores principales: Piliponsky, Adrian M., Sharma, Kavita, Quach, Phoenicia, Brokaw, Alyssa, Nguyen, Shayla, Orvis, Austyn, Saha, Siddhartha S., Samanas, Nyssa Becker, Seepersaud, Ravin, Tang, Yu Ping, Mackey, Emily, Bhise, Gauri, Gendrin, Claire, Furuta, Anna, Seo, Albert J., Guga, Eric, Miralda, Irina, Coleman, Michelle, Sweeney, Erin L., Bäuml, Charlotte A., Imhof, Diana, Snyder, Jessica M., Moeser, Adam J., Rajagopal, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9566924/
https://www.ncbi.nlm.nih.gov/pubmed/36006736
http://dx.doi.org/10.1172/JCI157999

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