Cargando…

Pregabalin for the treatment of generalized anxiety disorder

INTRODUCTION: Pregabalin is a treatement with a complexe mechanism of action. It’s an antiepileptic drug used as adjunctive treatment of partial epilepsy, it is also taken in the treatment of neuropathic pain, and generalized anxiety disorder, in addition to epilepsy. Some of the advantages of prega...

Descripción completa

Detalles Bibliográficos
Autores principales: Khallouk, A., Rhaouti, A., Boukdir, A., Stati, S., Nafiaa, H., Ouanass, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9567139/
http://dx.doi.org/10.1192/j.eurpsy.2022.1011
_version_ 1784809326954676224
author Khallouk, A.
Rhaouti, A.
Boukdir, A.
Stati, S.
Nafiaa, H.
Ouanass, A.
author_facet Khallouk, A.
Rhaouti, A.
Boukdir, A.
Stati, S.
Nafiaa, H.
Ouanass, A.
author_sort Khallouk, A.
collection PubMed
description INTRODUCTION: Pregabalin is a treatement with a complexe mechanism of action. It’s an antiepileptic drug used as adjunctive treatment of partial epilepsy, it is also taken in the treatment of neuropathic pain, and generalized anxiety disorder, in addition to epilepsy. Some of the advantages of pregabalin include. pharmacokinetics, safety, and tolerability. Clinical trials have demonstrated the efficacy of pregabalin comparable to benzodiazepines, without risk of abuse. OBJECTIVES: to assess the efficacy of pregabalin in patients with generalized anxiety disorder in the Ar-Razi university psychiatric hospital in Salé in Morocco METHODS: To assess the place of pregabalin in the treatement of anxiety disorders through patients hospitalized in the Ar-Razi university psychiatric hospital in Salé in Morocco The evaluation instruments are: For anxiety the Hamilton Anxiety Scale and For therapeutic efficacy CGI-therapeutic index RESULTS: based on the results of our study on the patients who have improved after an optimal duration of treatment, in conjunction with psychological monitoring, we retain that pregabalin can significantly improve the quality of life of anxious patients and also guarantee them a better prognosis CONCLUSIONS: Pregabalin was significantly more efficacious for the treatment of psychic and somatic symptoms of generalized anxiety disorder and was well tolerated by most study patients. DISCLOSURE: No significant relationships.
format Online
Article
Text
id pubmed-9567139
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cambridge University Press
record_format MEDLINE/PubMed
spelling pubmed-95671392022-10-17 Pregabalin for the treatment of generalized anxiety disorder Khallouk, A. Rhaouti, A. Boukdir, A. Stati, S. Nafiaa, H. Ouanass, A. Eur Psychiatry Abstract INTRODUCTION: Pregabalin is a treatement with a complexe mechanism of action. It’s an antiepileptic drug used as adjunctive treatment of partial epilepsy, it is also taken in the treatment of neuropathic pain, and generalized anxiety disorder, in addition to epilepsy. Some of the advantages of pregabalin include. pharmacokinetics, safety, and tolerability. Clinical trials have demonstrated the efficacy of pregabalin comparable to benzodiazepines, without risk of abuse. OBJECTIVES: to assess the efficacy of pregabalin in patients with generalized anxiety disorder in the Ar-Razi university psychiatric hospital in Salé in Morocco METHODS: To assess the place of pregabalin in the treatement of anxiety disorders through patients hospitalized in the Ar-Razi university psychiatric hospital in Salé in Morocco The evaluation instruments are: For anxiety the Hamilton Anxiety Scale and For therapeutic efficacy CGI-therapeutic index RESULTS: based on the results of our study on the patients who have improved after an optimal duration of treatment, in conjunction with psychological monitoring, we retain that pregabalin can significantly improve the quality of life of anxious patients and also guarantee them a better prognosis CONCLUSIONS: Pregabalin was significantly more efficacious for the treatment of psychic and somatic symptoms of generalized anxiety disorder and was well tolerated by most study patients. DISCLOSURE: No significant relationships. Cambridge University Press 2022-09-01 /pmc/articles/PMC9567139/ http://dx.doi.org/10.1192/j.eurpsy.2022.1011 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Khallouk, A.
Rhaouti, A.
Boukdir, A.
Stati, S.
Nafiaa, H.
Ouanass, A.
Pregabalin for the treatment of generalized anxiety disorder
title Pregabalin for the treatment of generalized anxiety disorder
title_full Pregabalin for the treatment of generalized anxiety disorder
title_fullStr Pregabalin for the treatment of generalized anxiety disorder
title_full_unstemmed Pregabalin for the treatment of generalized anxiety disorder
title_short Pregabalin for the treatment of generalized anxiety disorder
title_sort pregabalin for the treatment of generalized anxiety disorder
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9567139/
http://dx.doi.org/10.1192/j.eurpsy.2022.1011
work_keys_str_mv AT khallouka pregabalinforthetreatmentofgeneralizedanxietydisorder
AT rhaoutia pregabalinforthetreatmentofgeneralizedanxietydisorder
AT boukdira pregabalinforthetreatmentofgeneralizedanxietydisorder
AT statis pregabalinforthetreatmentofgeneralizedanxietydisorder
AT nafiaah pregabalinforthetreatmentofgeneralizedanxietydisorder
AT ouanassa pregabalinforthetreatmentofgeneralizedanxietydisorder