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Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes
Regulatory landscapes drive complex developmental gene expression, but it remains unclear how their integrity is maintained when incorporating novel genes and functions during evolution. Here, we investigated how a placental mammal-specific gene, Zfp42, emerged in an ancient vertebrate topologically...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9567273/ https://www.ncbi.nlm.nih.gov/pubmed/36179666 http://dx.doi.org/10.1016/j.cell.2022.09.006 |