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Correlation between psychotic risk and depressive “cognitive” symptoms in adolescence

INTRODUCTION: Prevention of disorders has become a central element of psychiatric research and clinic. Currently, Ultra High Risk (UHR) criteria are internationally recognized for psychiatric risk assessment. Self Disorders (SD) aroused particular interest because they were found to be specific to s...

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Autores principales: Maffucci, A., Cesario, S., Mammarella, V., Colafrancesco, G., Ferrara, M., Raballo, A., Monducci, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9567960/
http://dx.doi.org/10.1192/j.eurpsy.2022.1753
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author Maffucci, A.
Cesario, S.
Mammarella, V.
Colafrancesco, G.
Ferrara, M.
Raballo, A.
Monducci, E.
author_facet Maffucci, A.
Cesario, S.
Mammarella, V.
Colafrancesco, G.
Ferrara, M.
Raballo, A.
Monducci, E.
author_sort Maffucci, A.
collection PubMed
description INTRODUCTION: Prevention of disorders has become a central element of psychiatric research and clinic. Currently, Ultra High Risk (UHR) criteria are internationally recognized for psychiatric risk assessment. Self Disorders (SD) aroused particular interest because they were found to be specific to schizophrenic spectrum disorders and a marker of vulnerability for psychotic onset. OBJECTIVES: To evaluate the correlation between psychotic risk and depressive symptoms in at-risk adolescent population. METHODS: We collected data from 80 patients, aged 14-18, with sufficient skills in the Italian language and an IQ ≥70, excluding patients with disorders related to direct effects of a general medical condition or substance. Psychodiagnostic evaluation included K-SADS-PL, SIPS/SOPS, EASE (for the assessment of SDs) and the CDSS (for the assessment of Depression). RESULTS: 35 subjects have UHR criteria, while 45 do not have a psychotic risk syndrome or psychotic features. Between the two groups there is a significant difference in the total SCORE of EASE, in domains 1, 2 and 5. In addition, a positive correlation between SDs and depressive symptoms emerged, in particular with pathological guilt and with reference ideas of guilt. CONCLUSIONS: The results confirm the validity of SDs for early detection of psychosis. Depressive features appear to be associated with the presence of abnormalities of experience. This results suggest a close care and monitoring of depressive symptoms in adolescence, because they can mask disorders of different nature, particularly pathological guilt and guilty ideas of reference that are depressive “cognitive” symptoms more correlate with psychotic risk. DISCLOSURE: No significant relationships.
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spelling pubmed-95679602022-10-17 Correlation between psychotic risk and depressive “cognitive” symptoms in adolescence Maffucci, A. Cesario, S. Mammarella, V. Colafrancesco, G. Ferrara, M. Raballo, A. Monducci, E. Eur Psychiatry Abstract INTRODUCTION: Prevention of disorders has become a central element of psychiatric research and clinic. Currently, Ultra High Risk (UHR) criteria are internationally recognized for psychiatric risk assessment. Self Disorders (SD) aroused particular interest because they were found to be specific to schizophrenic spectrum disorders and a marker of vulnerability for psychotic onset. OBJECTIVES: To evaluate the correlation between psychotic risk and depressive symptoms in at-risk adolescent population. METHODS: We collected data from 80 patients, aged 14-18, with sufficient skills in the Italian language and an IQ ≥70, excluding patients with disorders related to direct effects of a general medical condition or substance. Psychodiagnostic evaluation included K-SADS-PL, SIPS/SOPS, EASE (for the assessment of SDs) and the CDSS (for the assessment of Depression). RESULTS: 35 subjects have UHR criteria, while 45 do not have a psychotic risk syndrome or psychotic features. Between the two groups there is a significant difference in the total SCORE of EASE, in domains 1, 2 and 5. In addition, a positive correlation between SDs and depressive symptoms emerged, in particular with pathological guilt and with reference ideas of guilt. CONCLUSIONS: The results confirm the validity of SDs for early detection of psychosis. Depressive features appear to be associated with the presence of abnormalities of experience. This results suggest a close care and monitoring of depressive symptoms in adolescence, because they can mask disorders of different nature, particularly pathological guilt and guilty ideas of reference that are depressive “cognitive” symptoms more correlate with psychotic risk. DISCLOSURE: No significant relationships. Cambridge University Press 2022-09-01 /pmc/articles/PMC9567960/ http://dx.doi.org/10.1192/j.eurpsy.2022.1753 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Maffucci, A.
Cesario, S.
Mammarella, V.
Colafrancesco, G.
Ferrara, M.
Raballo, A.
Monducci, E.
Correlation between psychotic risk and depressive “cognitive” symptoms in adolescence
title Correlation between psychotic risk and depressive “cognitive” symptoms in adolescence
title_full Correlation between psychotic risk and depressive “cognitive” symptoms in adolescence
title_fullStr Correlation between psychotic risk and depressive “cognitive” symptoms in adolescence
title_full_unstemmed Correlation between psychotic risk and depressive “cognitive” symptoms in adolescence
title_short Correlation between psychotic risk and depressive “cognitive” symptoms in adolescence
title_sort correlation between psychotic risk and depressive “cognitive” symptoms in adolescence
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9567960/
http://dx.doi.org/10.1192/j.eurpsy.2022.1753
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